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《Contemporary Medicine》 2017-35
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Ulinastatin and Mr Qu peptide curative effect in patients with severe acute pancreatitis and hemorrheology in learning

Xiao Xiu-ying;Xiao Jing-lei;Jiang Yong-feng;The Central People's Hospital of Ji'an City in Jiangxi province;  
Objective To explore the ulinastatin and Mr Qu peptide curative effect in patients with severe acute pancreatitis and hemorrheology in learning. Methods The clinical data of 80 patients with severe acute pancreatitis were retrospectively analyzed, on the basis of treatment the patients can be divided into two groups, namely the octreotide group(single treatment group, n=40) and the octreotide combined ulinastatin group(combination group, n=40), the hemorrheology in patients with two groups of learning, clinical curative effect, adverse reaction and death cases were analyzed. Results The combination therapy group of patients with thrombus length was significantly shorter than single treatment group(P0.05),than the whole blood high shear viscosity, plasma viscosity, platelet adhesion rate were significantly lower than that of single treatment group(P0.05), the total effective rate was 90.0%(36/40) was significantly higher than that of single treatment group was 70.0%(28/40)(P0.05), shock,DIC, acute nephritis, liver failure, adverse reactions such as pancreatic encephalopathy incidence and mortality were significantly lower than that of single treatment group(P0.05). Conclusion Ulinastatin combined the octreotide therapy can effectively improve hemorrheology in patients with severe acute pancreatitis, clinical curative effect is remarkable.
【CateGory Index】: R576
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