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《Academic Journal of Second Military Medical University》 2012-01
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RGD-modified polylactide-co-glycolic acid tissue engineering scaffolds for bone regeneration:an advance

TAO Chun,CHEN Yan,ZHONG Yan-qiang Department of Pharmaceutical Science,School of Pharmacy,Second Military Medical University,Shanghai 200433,China  
Polylactide-co-glycolic acid(PLGA) tissue engineering scaffolds play an important role in the regeneration of bone and cartilage.Due to the poor hydrophilicity of PLGA,it is difficult for cells to attach to the scaffolds.Modification by RGD(Arg-Gly-Asp) peptides can effectively improve the cellular affinity of PLGA and adhesion and proliferation of the seed cells.This review summarizes the recent progress in PLGA tissue engineering scaffolds modified by RGD peptides.
【Fund】: 国家自然科学基金(81072601)~~
【CateGory Index】: R318.08
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【Citations】
Chinese Journal Full-text Database 2 Hits
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【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 Hao Jie1 , Zheng Qixin2 , Guo Xiaodong2 ,etal.1.Department of Orthopaedic Surgery, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016;2.Department of Orthopedics, Union Hospital, Tongji Medical College of Huazhong Science and Technology University, Wuhan 430022;The Surface Modification and the Cellular Adhesion Study of PLGA-[ASP-PEG][J];Orthopaedic Biomechanics Materials and Clinical Study;2008-06
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