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《Academic Journal of Second Military Medical University》 2012-02
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Laparoscopic radical nephrectomy and open radical nephrectomy for stage T_2 renal cell carcinoma patients:a comparison of clinical outcomes

WANG Lin-hui,XU Zun-li,LIU Bing,YANG Qing,WU Zhen-jie,CHEN Wei,SHENG Hai-bo,SUN Ying-hao Department of Urology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China  
Objective To compare the efficacy of laparoscopic radical nephrectomy(LRN) and open radical nephrectomy(ORN) for clinical stage T_2 renal cell carcinoma.Methods A total of 138 patients underwent radical nephrectomy for renal cell carcinoma,including 63 by LRN and 75 by ORN.Renal cell carcinoma was pathologically confirmed in all the patients.The patients were followed up for 5-36 months,with a median of 24 months.The surgical blood loss,operation time,and time of starting food postoperatively,and hospital stay were compared between the two groups.Results The operation time was 90-385 min(a mean of 213±61.6 min) for LRN and 55-320 min(a mean of 173±52.3 min)for ORN(P=0.000).The blood loss was 30-1 600 ml(a mean of 220±291.8 ml) for LRN and 50-1 400 ml(a mean of 319±244.1 ml) for ORN(P=0.032).The fasting period of surgery was 1-4 d(a mean of 2.4±0.82 d) for LRN and 2-5 d(a mean of 3.1±1.02 d) for ORN(P=0.000).The hospital stay was 4-15 d(a mean of 7.3±2.50 d) for LRN and 6-15 d(a mean of 9.3±2.25 d) for ORN(P=0.000).Conclusion The efficacy of LRN is similar to that of ORN.LRN has the advantages of minimal invasiveness and rapid postoperative recovery.The complication of LRN is similar to ORN,and it might be an alternative treatment for clinical T_2 stage renal cell carcinomas.
【Fund】: 上海市市级医院新兴前沿技术联合攻关项目(SHDC12010115);; 上海市重点学科项目~~
【CateGory Index】: R737.11
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 XU Zun-li,WANG Lin-hui,CHEN Wei,YANG Qing,LIU Bing,WU Zhen-jie,SHENG Hai-bo,SUN Ying-hao Department of Urology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China;Transperitoneal versus retroperitoneal laparoscopic radical nephrectomy: a comparison of clinical outcomes[J];Academic Journal of Second Military Medical University;2011-09
2 WANG Lin-hui,SHENG Hai-bo,LIU Bing,YANG Qing,PENG Yong-han,WU Zhen-jie,CHEN Wei,XU Zun-li,SUN Ying-hao Department of Urology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China;Direct access to the renal artery for transperitoneal laparoscopic radical nephrectomy:the safety and feasibility[J];Academic Journal of Second Military Medical University;2011-09
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 WU Zhen-jie1,CAI Chen2,WANG Lin-hui 1,YANG Qing1,LIU Bing1,TANG Shou-yan1,CHEN Wei 1,SHENG Hai-bo1,WANG Cheng1,SUN Ying-hao1 1.Department of Urology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China 2.Department of Special Clinic,Changhai Hospital,Second Military Medical University,Shanghai 200433,China;Laparoendoscopic single-site(LESS)radical nephrectomy and standard laparoscopy:a comparison of therapeutic outcomes[J];Academic Journal of Second Military Medical University;2011-10
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Zhang Wei-wei,Cao Run-fu Department of Urology,the First Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi Province,China;Transperitoneal laparoscopic versus retroperitioneoscopic radical nephrectomy in renal cell carcinoma:A Meta-analysis[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2010-53
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