Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Academic Journal of Second Military Medical University》 2012-02
Add to Favorite Get Latest Update

Changes of monocyte chemoattractant protein-1 content in adenomyotic tissue and its significance

LI Juan1,2,WEN Ze-qing1,YIN Ge-ping2,CHEN Ming2,CHEN Ying-jian2 1.Department of Gynecology and Obstetrics,Provincial Hospital of Shandong,Shandong University School of Medicine,Ji'nan 250020,Shandong,China 2.Department of Gynecology and Obstetrics,General Hospital of Ji'nan Military Area Command,Ji'nan 250031,Shandong,China  
Objective To investigate the role of monocyte chemoattractant protein-1(MCP-1) in the pathogenesis of adenomyosis.Methods MCP-1 was examined by immunohistochemistry method and real-time PCR in the eutopic endometrium and ectopic endometrium of 36 patients with adenomyosis,and the results were compared with those of controls.Results MCP-1 contents in the eutopic endometrium and ectopic endometrium of patients with adenomyosis were significantly higher than those of normal controls(P0.05).The contents in ectopic endometrium tissue was significantly higher than that in eutopic endometrium tissue(P0.05),and the contents in the two tissues were significantly correlated with each other(r=0.87,P0.01). Conclusion MCP-1 may be involved in the pathogenesis of adenomyosis,but the specific molecular mechanisms need further study.
【CateGory Index】: R711.71
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 JIN Hai-yan,ZHOU Long-shu Department of Gynecology,Second Affiliated Hospital of Guangzhou Medical College,Guangzhou 510260,China;Ultrastructural change of the ectopic endometrium and its significance in endometriosis[J];Journal of Southern Medical University;2010-06
【Co-citations】
Chinese Journal Full-text Database 8 Hits
1 LI Nan-nan,ZHANG Zhi-min,WANG Cheng-kun,WANG Jin-rui,MENG Xiu-ping (Deparment of Endodontics and Operative Dentistry,Stomatology Hospital,Jilin University,Changchun 130021,China);Expression of MIP-1α mRNA in inflammed pulp tissue and its significance[J];Journal of Jilin University(Medicine Edition);2011-02
2 ZHAO Li-qiang,JIA Li-min,HE Ye-chun(Depantment of Orthopaedic,The Fifth Hospital of Harbin City,Harbin 150040,China);The Expression and Significance of MIP-1β and S-100 Protein in Human Colon Cancer[J];Heilongjiang Medical Journal;2007-03
3 WANG Zhong-cheng LIN Gui-jun (Department of Anatomy, Daqing Branch,Harbin Medical University, Heilongjiang Daqing 163319 China);The Expressions of S-100 Protein and RANTES in Tumor Tissues of B16 Melanoma Mice[J];Progress of Anatomical Sciences;2007-02
4 Ji Changwei~1 Ni Xiuqin~1 Jia Limin~2 Zhu Baoguo~1 Guo Wenguang~1 (1 Daqing Campus of Harbin Medical University,Daqing 163319; 2 Harbin Medical University,Harbin 150086,China);Expressions of E-cadhedn and S-100 protein in B16 melanoma tissue and their significance[J];Chinese Journal of Anatomy;2007-06
5 WANG Zhong-cheng (Department of Anatomy,Daqing Branch,Harbin Medical University,Daqing 163319,Heilongjiang,China);The Expression and Significance of S-100 Proteins and Nm 23 in Rats B16[J];Progress in Modern Biomedicine;2006-08
6 LIU Li~1 LIU Ying~2 WEI Lan JIA Li-min~2 HE Ye-chun~2 XIE Zun-jiang~2 (1 Department of Anatomy,Capital Medical University,Beijing 100069;2 Department of Anatomy,Harbin Medical University,Harbin,1500863;3 Institute for Environmental Health and Related Product Safety,Chinese Center for Disease Control and Prevention,Beijing,100021,China);Expressions of Heparanse and S-100 protein in gastric carcinoma of human[J];Progress in Modern Biomedicine;2008-12
7 Yong-Fang Jiang, Xian-Shi Su, Guo-Zhong Gong, Yan He, Yun Xu, Center for Liver Disease, Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China;Cloning and expression of murine CD40 ligand gene[J];World Chinese Journal of Digestology;2004-06
8 Yong-Fang Jiang,Yan He,Yong-Hong Zhang, Yun Xu,Guo-Zhong Gong, Research Center for Liver Disease, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China;Therapeutic effect of CD40 ligand gene on hepatocelluLar carcinoma in mice[J];World Chinese Journal of Digestology;2005-11
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved