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《Acta Academiae Medicine Militaris Tertiae》 2002-01
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Design and development of a software for an quartz crystal microbalance-based gene analyzer

HUANG Qing, LIU Ming hua, ZHANG Xue, HUANG Jun fu, CHEN Ming, JIANG Tian lun, ZHANG Bo, FU Wei ling (Department of Clinical Laboratories, Southwest Hospital, Third Military Medical University, Chongqing 400038, China)  
Objective To design and apply a software of the gene analyzer based on quartz crystal sensor array. Methods The frequency of the pieoelectric quartz crystal (PQC) resonance was detected and analyzed in real time with the software programmed with Microsoft Visual Basic Version 6.0 (VB6.0) and Microsoft Access 97 database. Results The designed software realized the detection of PQC frequency, data analysis and exchange, and result save in real time during the objective gene analysis. Conclusion The software for the gene analyzer is a new valid software that can detect and analyze the frequency of the PQC resonance, and should be widely used.
【Fund】: 国家“九五”科技攻关项目 (96 A2 3 0 4 0 4 );; 国家自然科学基金资助面上项目 (3 9870 83 1);; 国家高技术计划生物技术领域青年基金资助项目 (“863”项目 ;; 全军“九五”医学科研计划资助面上项目 (98MO94 );; 全军“十五”医学科研计划资助面上项目 (0 1MA180 )
【CateGory Index】: R197.39
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【References】
Chinese Journal Full-text Database 2 Hits
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【Citations】
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1 LIU Ming hua, FU Wei ling, WANG Song lin, HUANG Qing, WANG Jiang hua (Department of Laboratory Diagnosis, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Construction of piezoelectric gene sensor arrays[J];Acta Academiae Medicine Militaris Tertiae;2001-07
2 WANG Jianghua, FU Weiling, WANG Yingying, et al. Clinical Laboratory Department, South Western Hospital, Chongqing 400038, China;Application of piezoelectric genosensor techniques for rapid detection of human papillomavirus[J];CHINESE JOURNAL OF LABORATORY MEDICINE;2000-05
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【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHANG-Bo 1, FU Wei-ling 1, TANG Wan-li 2 (1.Southwest Hospital , Third Military Medical University,Chongqing 400038,China; 2.Dept of Bioengineering,China Jialing Group,Chongqing 400032,China);Development of piezoelectric quartz crystal biosensor's application research[J];Journal of Transducer Technology;2002-05
2 LIU Ming hua,FU Wei ling,CHEN Ming,et al. (Department of Medical Laboratory Science,Southwest Hospital,Third Military Medical University,Chongqing 400038);Effects of temperature on hybridization efficiency in piezoelectric gene sensor arrays[J];Chongqing Medical Journal;2001-06
3 LIU Ming hua, FU Wei ling, WANG Shong lin, HUANG Qing,CHEN Ming (Department of Medical Laboratory Science, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Effects of probe concentration on hybridization efficiency of piezoelectric gene sensor arrays[J];Acta Academiae Medicine Militaris Tertiae;2001-10
4 YU Fan,YIN Wei,XU Hua sheng,FU Wei ling,ZHANG Bo,JIANG Tian lun,CHEN Ming (Department of Study and Condition,the Twenty-Sixth Research Institute, Ministry of Information Industry,Chongqing 400060,China);Oscillation circuit of a quartz crystal microbalance-based gene analyzer[J];Acta Academiae Medicine Militaris Tertiae;2002-01
5 LIU Ming hua, FU Wei ling, XUE Qiang, HUANG Qing, WANG Song lin (Department of Clinical Laboratories, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Effects of target DNA chain length on hybridization efficiency with piezoelectric gene sensor[J];Acta Academiae Medicine Militaris Tertiae;2002-01
6 LIU Ming hua, FU Wei ling, ZHANG Xue, CHEN Ming, XUE Qiang (Department of Clinical Laboratories, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Effects of ionic strength on kinetic parameters of hybridization with piezoelectric gene sensor arrays[J];Acta Academiae Medicine Militaris Tertiae;2002-01
7 CHEN Ming,FU Wei ling,ZHANG Bo,JIANG Tian lun,YU Li li,LIU Ming hua,YU Fan,CHEN Xiao bing (Department of Clinical Laboratories, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Comparison between 2 probe immobilization methods on the surfaces of piezoelectric gene sensors[J];Acta Academiae Medicine Militaris Tertiae;2002-01
8 LIU Ming hua, FU Wei ling, CHEN Ming, HUANG Jun fu, HUANG Qing (Department of Clinical Laboratories, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Detection of methicillin-resistant Staphylococci aureus by piezoelectric gene sensor arrays[J];Acta Academiae Medicine Militaris Tertiae;2002-01
9 CHEN Ming, FU Wei ling, LIU Ming hua, ZHANG Bo, JIANG Tian lun, CHEN Qing hai,TANG Wan li, XU Shi jun, CAI Guo ru (Department of Clinical Laboratories, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Effects of pH values of buffer on hybridization efficiency with PNA piezoelectric gene sensor array[J];Acta Academiae Medicinae Militaris Tertiae;2003-15
10 ZHAO Meng, FU Wei-ling, CHEN Ming, XIA Han, LUO Yang, ZHAO Yu-hui, WANG Feng (Department of Clinical Laboratory Diagnosis, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Exponential decay regularity of frequency and endpoint determination by maximal-curvature in piezoelectric coagulation[J];Acta Academiae Medicinae Militaris Tertiae;2006-04
【Co-references】
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1 LIU Fang, LIU Zhongming, LI Jiazhou. Department of Medical Experiments, Guangzhou General Hospital of Guangzhou Command 510010;Comparision of Methods of Immobilization of Single-strand DNA on Surface of Quartz crystal[J];Beijing Biomedical Engineering;2003-02
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【Secondary References】
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1 MIN Cui-cuia,ZHOU Qib(a.School of Electronic Information and Automation;b.School of Bioengineering,Chongqing Institute of Technology,Chongqing 400050,China);Blood Coagulation Measuring Technology with Magnetoresistive Sensor[J];Journal of Chongqing Institute of Technology(Natural Science Edition);2008-01
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