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《Acta Academiae Medicine Militaris Tertiae》 2002-01
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Enhancement of anti-human bactericidal/permeability increasing protein (BPI) antibodies on bio-activities of porcine BPI in vitro

ZHOU Hong, ZHENG Jiang, QIN Xiao jian, XIAO Guang xia (Institute of Burn Research, Southwest Hospital, Third Military Medical University, Chongqing 400038, China)  
Objective To confirm the increasing abilities of anti human BPI polyclonal and monoclonal antibodies on bactericidal and endotoxin binding activities of porcine BPI. Methods Broth culture was used to observe the changes of bactericidal rate of porcine BPI with or without anti human BPI antibody. LAL test was used to test the ability of BPI binding to endotoxin after porcine BPI cultured with antibodies for 30 min. Results After anti human BPI polycolonal antibodies or monoclonal antibodies having no bactericidal activities were added, bactericidal rate of porcine BPI increased. But the antibody not against BPI had no such improving bactericidal activity. Meanwhile, anti human BPI polycolonal antibodies or monoclonal antibodies increased the binding ability of porcine BPI to endotoxin. Conclusion Anti human BPI polycolonal antibodies or monoclonal antibodies not only increase the bactericidal activity, but also increase the binding activity of porcine BPI to endotoxin.
【Fund】: 全军“九五”攻关课题 (96L0 4 2 )
【CateGory Index】: R392.11
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【References】
Chinese Journal Full-text Database 3 Hits
1 LI Yan-bing,GUI Yi,LI Jin-tao,LI Zuo-sheng,SHI Xian-wei,ZHANG Yi-fang(Faculty of Animal Science and Technology,Yunnan Agricultural University,Kunming 650201);Research Progress and Application Prospect of Bactericidal/Permeability Increasing Protein[J];China Animal Husbandry & Veterinary Medicine;2009-09
2 WEI Lin1,2,CHEN Bin1,ZHANG Shan-wen1,SONG Shen2,LIU Peng2(1.College of Animal Science and Technology,Hunan Agricultural University,Changsha 410128,China;2.The Department of Life Sciences in Huaihua College,Huaihua,Hunan 418008,China);Cloning of BPI gene from Qianshao spot pig and its amino acids sequence analysis[J];Journal of Hunan Agricultural University(Natural Sciences);2011-05
3 YE Lan1,ZI Chen1,LIU Lu1,ZHU Jing1,XIE Kai-Zhou1,ZHU Guo-Qian2,3,4,HUANG Xiao-Guo3,4,BAO Wen-Bin1,3,4,WU Sheng-Long1,3,4,WANG Jin-Yu1 1.Animal Science and Technology College,Yangzhou University,Key Laboratory for Animal Genetics,Breeding,Reproduction and Molecular Design of Jiangsu Province,Yangzhou 225009,China;2.College of Veterinary Medicine,Yangzhou University,Yangzhou 225009,China;3.Jiangsu Engineering Research Centre for Molecular Breeding of Breeder Pig,Changzhou 213149,China;4.Jiangsu(Yangzhou) Public Technical Service Centre for Efficient and Healthy Culture Technology in Large-scale Swine Farms,Yangzhou 225009,China;Study on the relationship between the expression of BPI gene and Escherichia coli F18 infection in piglets[J];Hereditas;2011-11
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LI Xiao-qi et al(Center of Animal Bio-technique,Sichuan Agricultural University,Yaan,Sichuan 625014);Cloning and Prokaryolic Expression of Rongchang Pig Porcine IL-10[J];Journal of Anhui Agricultural Sciences;2007-15
2 Qin Xiaojian, Zheng Jiang, Yuan Jiancheng, Liu Xiaolu, Xiao Guangxia (Institute of Burn Research, Southwest Hospital, Third Military Medical University, Chongqing,400038);Study of the bactericidal capability of BPI functional fragment in vitro[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;1999-09
3 KONG Pei yan, GUO Chao hua, LUO Cheng ji, ZHOU Yan hong, ZOU Zhong min, SHI Yan (Department of Hematology, Xinqiao Hospital, Third Military Medical University,Chongqing 400037,China);Effects of a combined cytokines on ex vivo expansion of BMMNC[J];Acta Academiae Medicine Militaris Tertiae;2001-10
4 Zheng Jiang, Zhou Hong, Xiao Guangxia (Research Institute of Burns, Southwest Hospital, Third Military Medical University, Chongqing, 400038);Therapeutic effects of pig bactericidal/permeability increasing protein on septicemia after burns in rats [J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;1998-03
5 Zheng Jiang, Yuan Jiancheng, Zhou Hong, Zhou Lixin, Liu Xiaolu, Xiao Guangxia (Research Institute of Burns, Southwest Hospital, Third Military Medical,Chongqing,400038);Studies on the anti endotoxin activity of modeling peptides of bactericidal/permeability increasing protein in vivo[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;1998-06
6 HUANG Jin-song, ZHENG Shao-yi, MAI Ming-jie, WU Ruo-bin Department of Cardiovasculelar Surgery, Guangdong Provincial People's Hospital, Guangzhou 510100, China;Transepicardial autologous transplantation of bone marrow mononuclear cells for acute myocardial infarction[J];Journal of Southern Medical University;2008-05
7 XUAN Xiong-biao,LUO Ting-rong,HUANG Wei-jian,ZENG Lan,ZHONG Qin(College of Animal Science and Technology,Guangxi University,Nanning,Guangxi,530005,China);Cloning and Sequence Analysis of INF-α_1 and INF-β_1 Genes in Swine[J];Progress in Veterinary Medicine;2006-04
8 Li Yan-qiu~* LI Xiao-li WANG Li-ning WANG-Yu LIU Xiao-dan LI Li QI Zan-mei JIANG Yi. *Department of Nephrology,The First Affiliated Hospital,China Medical University,Shenyang 110001,China;Granulocyte colony-stimulating factor gene polymorphism in patients with systemic lupus erythematosus in Northern Chinese[J];Chinese Journal of Rheumatology;2006-09
9 YAN Guang rong et al. (College of animal science and technology,Hu Nan Agricultural University, Chang Sha 410128);The Progress in Breeding of Animal Resistance Disease Using Molecular Marker[J];Animal Science Abroad;2001-06
10 QI Ke-zong,CHENG Yu-lei,TU Jian (College of Animal Technology,Anhui Agricultural University,Hefei 230036,China);Cloning and identification of chicken and pig BPI protein N-terminal fragment[J];Journal of Guangxi Agricultural and Biological Science;2006-S1
【Secondary References】
Chinese Journal Full-text Database 3 Hits
1 LI Fu-quan1,2,YANG Wen2,GUO Bin3,HUO Jin-long4,SHI Xian-wei1(1.Center of Biodiversity and Biotechnology,College of Animal Science and Technology, Yunnan Agricultural University,Kunming 650201,China; 2.Department of Biotechnology,Neijiang Vocational & Tecnical College,Neijiang,641100,China; 3.College of Animal Science and Veterinary Medicine,Jilin University,Changchun 130062,China; 4.Key Laboratory of Bamma Mini-Pig Inbred Line of Yunan Province,Kunming 650201,China);SNPs Detection of PLTP-4 among Dahe Blank Porcine and Association Analysis with their Production Performance[J];China Animal Husbandry & Veterinary Medicine;2013-07
2 YE Lan1,ZI Chen1,LIU Lu1,ZHU Jing1,XIE Kai-Zhou1,ZHU Guo-Qian2,3,4,HUANG Xiao-Guo3,4,BAO Wen-Bin1,3,4,WU Sheng-Long1,3,4,WANG Jin-Yu1 1.Animal Science and Technology College,Yangzhou University,Key Laboratory for Animal Genetics,Breeding,Reproduction and Molecular Design of Jiangsu Province,Yangzhou 225009,China;2.College of Veterinary Medicine,Yangzhou University,Yangzhou 225009,China;3.Jiangsu Engineering Research Centre for Molecular Breeding of Breeder Pig,Changzhou 213149,China;4.Jiangsu(Yangzhou) Public Technical Service Centre for Efficient and Healthy Culture Technology in Large-scale Swine Farms,Yangzhou 225009,China;Study on the relationship between the expression of BPI gene and Escherichia coli F18 infection in piglets[J];Hereditas;2011-11
3 WU Zheng-chang 1,WANG Jing 1,ZHU Shi-ping 1,ZHAO Qiao-hui 1,LIU Lu 1,ZI Chen 1,WU Sheng-long 1,2*,BAO Wen-bin 1,2*(1.Key Laboratory for Animal Genetics,Breeding,Reproduction and Molecular Design of Jiangsu Province,College of Animal Science and Technology,Yangzhou University,Yangzhou225009,China;2.Jiangsu Engineering Research Centre for Molecular Breeding of Breeder Pig,Changzhou213149,China);The Partial cSNPs Detection of Pig BPI Gene and Its Influence on Protein Structure and Function[J];Chinese Journal of Animal and Veterinary Sciences;2013-07
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