Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Acta Academiae Medicinae Militaris Tertiae》 2006-13
Add to Favorite Get Latest Update

Localization of neural specific transcription factor LMO3 mRNA in adult mouse central nervous system

HUI Ling~(1,2),CAI Wen-qin~1,LU Tong-de~2(~1Department of Neurobiology,College of Medicine,Third Military Medical University,Chongqing 400038;~(2)Laboratory Center of Medical Sciences,Lanzhou General Hospital,Lanzhou Military Command Area,Lanzhou 730050,China)  
Objective To explore the localization of neural specific transcription factor LMO3 mRNA in the central nervous system of the mice.Methods Five male adult mice,weighing 60-80 g,were sacrificed,and the brain and spinal cord were fixed and sliced.In situ hybridization histochemistry staining method with digoxigen-lablled cRNA probe was used in detection of LMO3 mRNA.Results The expression of LMO3 mRNA could be observed in cerebrum,cerebellum,thalamus,brain stem and spine.They were localized in somatic and dendritic profiles at most regions of adult mouse central nervous system.The intense hybridization signal could be seen in Ⅱ-Ⅵ layers of cerebrum,piriform cortex,entorhinal cortex,hippocampus CA1 and dentate gyrus,substantia nigra,motor nucleus of trigeminus,nucleus of hypoglossal,red nucleus,paraventricular nucleus,gigantocellular reticular nucleus,lateral reticular nucleus.The moderate staining was detected in olfactory bulb,hippocampal CA2,amygdala nucleus,cingulated anterior cortex,piriform nucleus etc..The faint signal showed in globus pallidus,spinal nucleus of trigeminal,interposed cerebellar nucleus,ambiguous nucleus,lateral cerebellar nucleus,Purkinje cell of cerebellum,thalamus,caudate putamen,amygdaloid body,nuclei raphe.Conclusion The wide presence of LMO3 mRNA in adult mice central nervous system suggests a role of regulation for this gene in learning,memory and olfaction besides in dopamine neurotransmitter regulation.
【Fund】: 国家自然科学基金面上项目青年基金资助项目(30400125)~~
【CateGory Index】: Q343
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 2 Hits
1 LI Dian-wei~(1,2),LI Jia-wei~(1,3),Ding Yong-zhong~4,Zhao Zhi-hua~1, L(U|¨) Tong-de~1,Yang Jin-sheng~1,HUI Ling~1 (1.Expermental Center of Medicine,Lanzhou General Hospital of Lanzhou Military Command, Lanzhou 730050,China;2.Department of Neurosurgery,First People's Hospital of Lanzhou City, Lanzhou 730050,China;3.School of Life Sciences,Lanzhou University,Lanzhou 730000,China; 4.Department of Neurosurgery,Second Hospital of Lanzhou University,Lanzhou 730030,China);Expression and significance of LMO3 gene in human glioma[J];Journal of Lanzhou University(Medical Sciences);2009-03
2 HUI Linga,L Tong-dea*,WANG Jian-fenga,WANG Xiao-huia, HA Xiao-qina,ZHANG Jun-lia,YANG Gui-lanb,JU Yingb (a. Experimental Center of Medicine,Key Laboratory of Stem Cells and Gene Drug of Gansu Province; b. Dermatology Department,General Hospital of Lanzhou Military Command,Lanzhou 730050,Gansu,China);Overexpression of LMO3 Increases Proliferation of Glia Cells[J];Life Science Research;2010-02
【Citations】
Chinese Journal Full-text Database 1 Hits
1 HUI Ling+1, CAI Wen-qin 1* , SHI Jun+2, LI Wei+1(1.Department of Histology and Embryology,the Third Military Medical University Chongqing;2^Neurosurgery of the Xingqiao Hospital of the Third Military Medical University,Chongqing 400038,China);THE LOCALIZATION OF NEURONAL SPECIFIC TRANSCRIPTION FACTOR DAT1 mRNA IN ADULT RAT CENTRAL NERVOUS SYSTEM[J];Acta Anatomica Sinica;2004-02
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 HUI Ling 1, JI Chao-neng 2, CAI Wen-qin 1, GU Shao-hua 2, YING Kang 2, XIE Yi 2, MAO Yu-min 2 ( 1Department of Histology and Embryology, College of Medicine, Third Military Medical University, Chongqing 400038; 2Institute of Genetics, College of Life Sciences, Fudan University, Shanghai 200433, China);Identification of DAT1/LIM2-interacting proteins by yeast two-hybrid screening[J];Acta Academiae Medicinae Militaris Tertiae;2005-05
2 HUI Ling 1 , WANG Xiao-hui 1 ,YUAN Bi-bo 2 , YANG Jin-kai1, LU Tong-de 1 , HUI Bin 3 , CAI Wen-qin 2 ( 1 Experimental Center of Medicine, Lanzhou General Hospital of Lanzhou Command, Lanzhou 730050; 2 Department of Histology and Embryology, Third Military Medical University, Chongqing 400038; 3 Pharmacology Research Center of Shanghai Medical College, Fudan University, Shanghai 200032, China);Construction of eukaryotic expression of CIB vectors and its expression in NIH3T3 cells[J];Acta Academiae Medicinae Militaris Tertiae;2007-03
3 HUI Ling~1, CAI Wen-Qin~2, JI Hua~3, L Tong-De~1, YANG Jin-Sheng~1, ZHAO Zhi-Hua~1 ~1Experimental Center of Medicine, Lanzhou General Hospital, Lanzhou Military Area Command, Lanzhuo 730050, China, ~2Department of Neurobiology, ~3Department of Histology and Embryology, Third Military Medical University, Chongqing 400038, China;Expression changes of LMO3 mRNA during mouse brain development[J];Journal of the Fourth Military Medical University;2006-24
4 LI Dian-wei~(1,2),LI Jia-wei~(1,3),Ding Yong-zhong~4,Zhao Zhi-hua~1, L(U|¨) Tong-de~1,Yang Jin-sheng~1,HUI Ling~1 (1.Expermental Center of Medicine,Lanzhou General Hospital of Lanzhou Military Command, Lanzhou 730050,China;2.Department of Neurosurgery,First People's Hospital of Lanzhou City, Lanzhou 730050,China;3.School of Life Sciences,Lanzhou University,Lanzhou 730000,China; 4.Department of Neurosurgery,Second Hospital of Lanzhou University,Lanzhou 730030,China);Expression and significance of LMO3 gene in human glioma[J];Journal of Lanzhou University(Medical Sciences);2009-03
5 HUI Ling, CAI Wen-qin,LU Tong-de.(Experimental Center of Medicine, Lanzhou General Hospital, Lanzhou Command, PLA, 730050, China);Construction of recombinant DAT1/EGFP vectors and its expression in C8 cells[J];Medical Journal of National Defending Forces In Northwest China;2005-03
【Co-references】
Chinese Journal Full-text Database 5 Hits
1 HUI Ling 1, JI Chao-neng 2, CAI Wen-qin 1, GU Shao-hua 2, YING Kang 2, XIE Yi 2, MAO Yu-min 2 ( 1Department of Histology and Embryology, College of Medicine, Third Military Medical University, Chongqing 400038; 2Institute of Genetics, College of Life Sciences, Fudan University, Shanghai 200433, China);Identification of DAT1/LIM2-interacting proteins by yeast two-hybrid screening[J];Acta Academiae Medicinae Militaris Tertiae;2005-05
2 HUI Ling 1, LIU Jian-jun 1, YAO Zhong-xiang 1, CAI Wen-qin 2 ( 1Department of Histology and Embryology, 2Department of Neurobiology, College of Medicine, Third Military Medical University, Chongqing 400038, China);Effects of DAT1 gene on differentiation of neural stem cells in rats[J];Acta Academiae Medicinae Militaris Tertiae;2005-07
3 HUI Ling~1, CAI Wen-Qin~2, JI Hua~3, L Tong-De~1, YANG Jin-Sheng~1, ZHAO Zhi-Hua~1 ~1Experimental Center of Medicine, Lanzhou General Hospital, Lanzhou Military Area Command, Lanzhuo 730050, China, ~2Department of Neurobiology, ~3Department of Histology and Embryology, Third Military Medical University, Chongqing 400038, China;Expression changes of LMO3 mRNA during mouse brain development[J];Journal of the Fourth Military Medical University;2006-24
4 HUI Ling+1, CAI Wen-qin 1* , SHI Jun+2, LI Wei+1(1.Department of Histology and Embryology,the Third Military Medical University Chongqing;2^Neurosurgery of the Xingqiao Hospital of the Third Military Medical University,Chongqing 400038,China);THE LOCALIZATION OF NEURONAL SPECIFIC TRANSCRIPTION FACTOR DAT1 mRNA IN ADULT RAT CENTRAL NERVOUS SYSTEM[J];Acta Anatomica Sinica;2004-02
5 HUI Ling 1,2 ,CAI Wen-qin 2 ,LU Tong-de 1 ,WANG Ling 3(1.Expermental Center of Medicine,Gen eral Hospital of Lanzhou Military Co mmand,Lanzhou730050,Gansu,China;2.Department of Histology and Embryology,the Third Military Medical Univ ersity,Chongqing400038,China;3.Lanzhou City First People Hospital,Lanzhou730050,Gansu,China);The Expression of Neuronal Specific Transcription Factor DAT1[J];Life Science Research;2005-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved