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《Acta Academiae Medicinae Militaris Tertiae》 2006-13
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Long serial analysis of gene expression in hyphal cells of Candida albicans

ZHOU Cun-jian,DENG Yong-jian,HAO Fei,ZHONG Bai-yu,WANG Lu,LI Yong-ping(Department of Dermatology,Southwest Hospital,Third Military Medical University,Chongqing 400038,China)  
Objective To observe the characteristics of gene expression in the hyphal cells of Candida albicans. Methods A LongSAGE library was established with long serial analysis of gene expression(LongSAGE).After the clones from the LongSAGE library were sequenced,the results were analyzed by SAGE software and compared with the SAGE map at NCBI.Results A total of 17 552 tags,representing 6 627 genes or EST,were extracted from the 1 000 sequence files of the hyphal cells of Candida albicans.Fifteen of thirty-six tags which expression frequency exceeded thirty-five may be new expressed sequences.Conclusion LongSAGE technology can be used not only in understanding the quantity information of gene expression,but also in finding new genes.
【Fund】: 国家自然科学基金资助项目(30200013)~~
【CateGory Index】: R379;Q78
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Chinese Journal Full-text Database 1 Hits
1 ;Hypha formation of Candida albicans by induced culture[J];Acta Academiae Medicinae Militaris Tertiae;2004-09
Chinese Journal Full-text Database 5 Hits
1 LIU Zhi-chun1a,MA Lian-lan1a,WU Xiao-yun1b,HUANG Can1c,LUO Chun-yan1c(1a.The Department of Pathogenic Biology,Gannan Medical University;1b.The Department of Biochemistry and Molecular Biology,Gannan Medical University;1c.Student of clinical undergraduate,Gannan Medical University,Gangzhuo Jiangxi 341000);Effects of KZY-2 compound on bud formation in Candida albicans[J];Journal of Gannan Medical University;2008-04
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4 HUANG Wei,YANG Yi-cheng,HUANG Chang-zheng,et al(Department of Dermatology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China);Dendritic Cells Pulsed with Hyphae and Yeasts of Candida albicans and the Role in Experimental Mouse Systematic Candidiasis[J];The Chinese Journal of Dermatovenereology;2008-07
5 ZHOU Cun-jian, HAO Fei DENG Yong-jian, WANG Li, ZHONG Bai-yu, LI Yong-ping. Department of Dermatology, Third Military Medical College, Chongqing 400038, China;Long serial analysis of gene expression of different phases of Candida albicans[J];Chinese Journal of Microbiology and Immunology;2006-06
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