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《Acta Academiae Medicinae Militaris Tertiae》 2006-13
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Interventional therapy for infective endocarditis and patent ductus arteriosus

SHU Mao-qin,SONG Zhi-yuan,ZHONG Li,HE Guo-xiang,LI Yong-hua,ZHUANG Guo-qiang(Department of Cardiology,Southwest Hospital,Third Military Medical University,Chongqing 400038,China)  
Objective To explore the diagnostic and therapeutic methods of infective endocarditis.Methods The literature data in recent years of the diagnosis and treatment for infective endocarditis were reviewed.The therapeutic experience of Amplatzer procedure in 1 case of infective endocarditis associated with patent ductus arteriosus was analyzed.Results The predominant pathogenic bacteria were Gram-positive cocci in over 2-year-old patients.Penicillin-resistant streptococcus was not found.All kinds of staphylococcus aureus were sensitive to vancomycin.The antibiotic preference was a large dose of penicillin or penicillin combined with aminoglycosides.Early surgical treatment,which corrected the abnormality of heart structure and cleared vegetations or infective focus,was a key measure for the decrease of mortality.In our report,this patient with infective endocarditis associated with patent ductus arteriosus had no visible vegetation in ultrasound examination,and underwent Amplatzer intervention therapy after application of norvancomycin.A good clinical result was obtained in the patient.Conclusion A key therapy is a large dose of sensitive antibiotics and surgery as early as possible.The interventional therapy may be one of effective tools.
【CateGory Index】: R725.4
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