Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Acta Academiae Medicinae Militaris Tertiae》 2006-24
Add to Favorite Get Latest Update

Metrological study on damaging effect of steep pulsed electric field on fresh excised calf liver

YU Jin-mei 1,XIONG Zheng-ai 1,LING Xiao-juan 1,SUN Cai-xin 2,YAO Chen-guo 2,HONG Chuan 2,MO Deng-bin2,MI Yan 2,WANG Shi-bin 2(1Department of Obstetrics and Gynecology,The Second Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400010;2Key Lab of High Voltage Engineering and Electrical New Technology of Ministry of Education,Chongqing University,Chongqing 400044,China)  
Objective To study the damaging effect of steep pulse on fresh excised calf liver.Methods Fresh excised calf liver tissues were exposed to steep pulsed electric fields set at different voltage,different time or different frequency,then the necrotic tissue diameter was measured.B-mode imaging was used to visualize the gray changes before and after steep pulse exposure.TTC and histological examination were used to observe the damaging effect.The temperature of the damaged tissues was measured.Results The damaged tissues were of coagulation necrosis by TTC and histological examination.The necrotic tissue diameter increased with the increasing of voltage,time and frequency of steep pulses.The temperature changes were not statistically significant before and after steep pulse exposure(P0.05).Conclusion There is apparent dose-response relation in calf liver coagulation necrosis induced by steep pulses and the necrosis diameter.
【Fund】: 国家自然科学基金资助项目(50477007)~~
【CateGory Index】: R312
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 5 Hits
1 XIANG Peng1,3,LI Cheng-Xiang1,LIAO Rui-Jin1,YAO Chen-Guo1,MI Yan1,XIONG Zheng-Ai2,GU Hua-Yan2(1.The State Key Laboratory of Power Transmission Equipment & System Security and New Technology,Chongqing University,Chongqing 400044,China;2.Second Affiliated Hospital Chongqing Medical Science University,Chongqing 400061,China;3.No.77118 Hospital of PLA,Chengdu 618408,China);Electric Intensity Threshold of Irreversible Electric Breakdown of Rabbit Liver VX_2 Tumor Under Steep Pulse Electric Field[J];High Voltage Engineering;2008-10
2 LING Xiao-juan1,ZHANG Chen-ling1,XIONG Zheng-ai2,LI Cheng-xiang3,YAO Chen-guo3(1.Department of Gynaecology and Obstetrics,Baoji Central Hospital,Baoji 721008,Shanxi,China;2.Department of Gynaecology and Obstetrics,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010;3.The Key Laboratory of High Voltage and Electrical New Technology,Ministry of Educ,Chongqing University,Chongqing 400044,China);Study on dose of steep pulsed electric fields in rabbit liver[J];Biomedical Engineering and Clinical Medicine;2010-02
3 Wu Jianxing1,Yang Hongchun1,Yang Xiaolin1,Zhang Yi2,Zeng Gang1,Zhang Xiaoyu1(1.Physical Electronics College,University of Electronics Science and Technology of China,Chengdu 610054,China; 2.West China Women's and Children's Hospital,Sichuan University,Chengdu 610041,China);Development of sub-microsecond pulser applied for electroporation effect[J];Experimental Technology and Management;2012-05
4 Tan Yafang1 Yang Hongchun1 Wu Jianxing1 Yang Xiaolin1 Zhang Yi2 Zeng Gang1 Zhang Xiaoyu1 1(Physical Electronics College,University of Electronics Science and Technology of China,Chengdu 610054,China) 2(West China Women's and Children's Hospital,Sichuan University,Chengdu 610041,China);The Sub-Microsecond Pulser Applied for Electroporation Effect[J];Journal of Biomedical Engineering;2012-04
5 WUJing1,XIONG Zheng-ai1,LI Cheng-xiang2,YAO Cheng-guo2,SUN Cai-xin2,YANG Xiao-yan1,ZHAO Dong-yang21. Department of Obstetrics and Gynecology,The Second Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400010,China;2. Key Lab of High Voltage Engineering and Electrical New Technology of Ministry of Education,Chongqing University,Chongqing 400044,China;An Experimental Study of the Effects of Steep Pulse Treatment on Liver Cancer of Rabbit Monitored by Ultrasound[J];Journal of Southwest University(Natural Science Edition);2009-01
【Citations】
Chinese Journal Full-text Database 5 Hits
1 HU Ya, HU Li na, MI Yan, YAO Cheng guo, XIONG Lan, SUN Cai xin (Department of Obstetrics and Gynecology, Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China);Effects of the energy controllable steep pulses on human ovarian carcinoma cell in vitro[J];Acta Academiae Medicinae Militaris Tertiae;2003-16
2 YAO Chen-guo, SUN Cai-xin, XIONG Lan, MI Yan, WANG Shi-bin Under the State Ministry of Education, Chongqing University, Chongqing 400030, China);Irreversible Electrical Breakdown of Malignant Tumor Cell Under Steep Pulsed Electric Fields[J];Journal of Chongqing University(Natural Science Edition);2004-06
3 Hu Yong Yu Jie (College of Precision Instrument and Optical Electronic Engineering, Tianjing University, Tianjing 300072);A Study on Distribution Modeling of the Electrical Stimulation under Surface Nerve Stimulation Electrodes for Somatosensory Evoked Potential[J];JOURNAL OF BIOMEDICAL ENGINEERING;1999-04
4 YAO Chen-guo1, SUN Cai-xin1, MI Yan1, XIONG Lan1, LIAO Rui-jin1, HU Li-na2, HU Ya2 (1. Key Lab of High Voltage Engineering and Electrical New Technology, Ministry of Education, Chongqing 400044; 2. Second Affiliated Hospital, Chongqing Medical Science University, Chongqing 400061);EXPERIMENTAL STUDY ON IRREVERSIBLE ELECTRICAL BREAKDOWN OF MALIGNANT TUMOR CELL UNDER STEEP PULSE[J];Chinese Journal of Biomedical Engineering;2004-01
5 YAO Chen-guo 1, SUN Cai-xin 1, MI Yan 1, XIONG Lan 1, HU Ya 2, HU Li-na 2 (1.Key Lab of Ministry of Education for High Voltage Engineering and Electrical New Technology, Chongqing Universify,Chongqing 400044; 2.Second Affiliated Hospital, Chongqing Medical Science University, Chongqing 400010);EXPERIMENTAL STUDY OF LETHAL AND INHIBITORY EFFECTS ON TUMOR-BEARING MICE UNDER STEEP PULSED ELECTRIC FIELD[J];Chinese Journal of Biomedical Engineering;2004-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LI Jun1, YANG Xiao-Jun1, HU Li-Na1, SUN Cai-Xin2, YAO Chen-Guo2 1. Department of Gynecology and Obstetrics, The Second Affiliated Hospital, Chongqing University of Medical Science, Chongqing, 400010, P. R. China 2. Key Laboratory of Voltage Engineering and Electrical New Technology of Ministry of Education, Chongqing University, Chongqing, 400044, P. R. China;Impacts of Steep Pulsed Electric Fields on Lymphatic Capillaries in VX_2 Implanted Breast Cancer in Rabbits[J];Chinese Journal of Cancer;2006-02
2 Xiao-Jing Dong,1 Li-Na Hu,1 Yun-Shan Zhu,1 Chuan Hong,2 Cong Li1 and Xiao-Dong Luo11.Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400010, P.R.China 2.Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, P.R.China 3.Key Laboratory of Voltage Engineering and Electrical New Technology of Ministry of Education, Chongqing University, Chongqing, 400044, P.R.China;Effects of energy controllable steep pulses on intracellular calcium concentration and cell membrane potential[J];Chinese Journal of Cancer;2009-09
3 WANG Ping-ling 1, HU Li-na 1, LI Cong 1, SUN Cai-xin 2, MI Yan 2, WANG SHI-bin 2, YAO Cheng-guo 2 ( 1Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Chongqing University of Medical Science, Chongqing 400016; 2Key Lab of High Voltage Engineering and Electrical New Technology, Ministry of Education, Chongqing 400044, China);Experimental study of energy controllable steep pulses and RNA interference targeting H-ras gene on inhibiting growth of xenografted tumor of ovarian cancer cells[J];Acta Academiae Medicinae Militaris Tertiae;2005-06
4 HU Ya~(1), HU Li-na~(2), MI Yan~(3), YAO Cheng-guo~(3), XIONG Lan~(3), SUN Cai-xin~(2) ( ~(1)Department of Obstetrics and Gynecology, No. 324 Hospital of PLA, Chongqing 400020; ~(2)Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Huaxi Medical College, Sichuan University, Chengdu 610041; ~( 3)College of Electrical Engineering, Chongqing University, Chongqing 400044, China);Lethal effects of energy controllable steep pulses on U_(14) cervical cancer in mice[J];Acta Academiae Medicinae Militaris Tertiae;2005-17
5 LUO Xiao-dong 1 , HU Li-na 1 , SUN Cai-xin 2 , YAO Chen-guo 2 , XIONG Lan 2 , MI Yan 2 , WANG Shi-bin 2 ( 1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital,Chongqing University of Medical Sciences, Chongqing 400016, 2 Key Lab of High Voltage Engineering and New Electrical Technology, Chongqing University, Chongqing 400044, china);Effects of energy controllable steep pulse on human umbilical vein endothelial cells in vitro[J];Acta Academiae Medicinae Militaris Tertiae;2005-21
6 DONG Xiao-jing 1 , HU Li-na 3 , SUN Cai-xin 2 , ZHU Yun-shan 1 , HONG Chuan 2 , LI Cong 1 , LUO Xiao-dong 1 , MI Yan 2 ( 1 Department of Obstetrics and Gynecology, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010; 2 Key Laboratory of Voltage Engineering and Electrical New Technology, College of Electrical Engineering, Chongqing University, Chongqing 400044, 3Department of Obsterics and Gynecology, Huaxi Second Hospital, Sichuan University, Chengdu 610041, China);Dosage and safety evaluation of energy controllable steep pulse in treatment of implanted rabbit tumors[J];Acta Academiae Medicinae Militaris Tertiae;2007-03
7 WU Xiao-juan1, YAO Zhen-wei1,TANG Jun-ying1, YAO Chen-guo2, SUN Cai-xin2 (1Department of Gynecology and Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016; 2 Key Laboratory of High Voltage and Electrical New Technology of Ministry of Education, College of Electrical Engineering, Chongqing University, Chongqing 400044, China);Growth inhibition and apoptosis induction of nanosecond steep pulse on human ovarian carcinoma cell line SKOV_3[J];Acta Academiae Medicinae Militaris Tertiae;2007-17
8 LI Cong1,HU Li-na 1,2,DONG Xiao-jing1,SUN Cai-xin3,MI Yan 3(1Department of Obstetrics and Gynecology,The Second Affiliated Hospital,Chongqing Medical University,Chongqing 400016;2 Department of Obstetrics and Gynecology,The Second Affiliated Hospital,West China Hospital,Sichuan University,Chengdu 610081;3Key Laboratory of High Voltage and New Electrical Techniques of Ministry of Education,College of Electrical Engineering,Chongqing University,Chongqing 400044,China);Ovarian cancer cell apoptosis by high intensity electric pulses:mitochondrial mechanism[J];Acta Academiae Medicinae Militaris Tertiae;2008-13
9 Zhou Wei1,Xiong Zheng'ai1,Liu Ying1,Li Chengxiang2,Yao Chenguo2(1Department of Gynecology and Obstetrics,Second Affiliated Hospital,Chongqing Medical University,Chongqing,400010;2State Key Laboratory of Power Transmission Equipment and System Security and New Technology,Chongqing University,Chongqing,400030,China);Apoptosis and necrosis of HeLa cells induced by irreversible electroporation[J];Acta Academiae Medicinae Militaris Tertiae;2010-18
10 LUO Xiao-dong 1 , HU Li-na 1 , SUN Cai-xin 2 , YAO Chen-guo 2 , XIONG Lan 2 , MI Yan 2 , WANG Shi-bin 2 (1.Department of Obstetrics and Gynecology, the Second Affilate Hospital, Chongqing University of Medical Science, Chongqing 400010, China; 2. Key Laboratory of High Voltage Engineering and Electrical New Technology Under the State Ministry of Education,Chongqing University, Chongqing 400030, China);Experimental Study of Energy Controllable Steep Pulse in the Treatment of Rat with Subcutaoneous Transplantive Tumor[J];Journal of Chongqing University(Natural Science Edition);2005-07
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LI Jun1, YANG Xiao-Jun1, HU Li-Na1, SUN Cai-Xin2, YAO Chen-Guo2 1. Department of Gynecology and Obstetrics, The Second Affiliated Hospital, Chongqing University of Medical Science, Chongqing, 400010, P. R. China 2. Key Laboratory of Voltage Engineering and Electrical New Technology of Ministry of Education, Chongqing University, Chongqing, 400044, P. R. China;Impacts of Steep Pulsed Electric Fields on Lymphatic Capillaries in VX_2 Implanted Breast Cancer in Rabbits[J];Chinese Journal of Cancer;2006-02
2 CHEN Xiang, WANG Hong-lin,LI Jian, et al. (Department of Hepatobiliary Surgery, the First Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400016,China);Effect of radio-frequency ablation combinated with epirabicin on microvessel density and PCNA in rabbit hepatcocellular carcinoma models[J];Chongqing Medical Journal;2005-12
3 ZHANG Hong 1 WANG Bao-yi 1 CHEN Hai-chuan 1 WANG Zi-shu 2 YANG Kong 2 SUN Jing-ru 2 (1 College of Electron-information, Sichuan University, Chengdu Sichuan 610064 China;2 College of Life Science, Sichuan University, Chengdu Sichuan 610064, China);An experiment studies to the treatment of sarcomas by the electroporation therapy[J];Chinese Journal of Radio Science;2003-03
4 ZHA Shen-sen,ZHENG Jian-yong,SU Lin,WU Heng-rong, CHEN Jun ( Southeast University,Nanjing 210096,China; Jiangsu Huaxia Electrical Company , Yangzhong 212200, China );Research on dynamic voltage balancing of serial IGBTs[J];Electric Power Automation Equipment;2005-05
5 HU Ya, HU Li na, MI Yan, YAO Cheng guo, XIONG Lan, SUN Cai xin (Department of Obstetrics and Gynecology, Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China);Effects of the energy controllable steep pulses on human ovarian carcinoma cell in vitro[J];Acta Academiae Medicinae Militaris Tertiae;2003-16
6 HU Ya~(1), HU Li-na~(2), MI Yan~(3), YAO Cheng-guo~(3), XIONG Lan~(3), SUN Cai-xin~(2) ( ~(1)Department of Obstetrics and Gynecology, No. 324 Hospital of PLA, Chongqing 400020; ~(2)Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Huaxi Medical College, Sichuan University, Chengdu 610041; ~( 3)College of Electrical Engineering, Chongqing University, Chongqing 400044, China);Lethal effects of energy controllable steep pulses on U_(14) cervical cancer in mice[J];Acta Academiae Medicinae Militaris Tertiae;2005-17
7 LUO Xiao-dong 1 , HU Li-na 1 , SUN Cai-xin 2 , YAO Chen-guo 2 , XIONG Lan 2 , MI Yan 2 , WANG Shi-bin 2 ( 1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital,Chongqing University of Medical Sciences, Chongqing 400016, 2 Key Lab of High Voltage Engineering and New Electrical Technology, Chongqing University, Chongqing 400044, china);Effects of energy controllable steep pulse on human umbilical vein endothelial cells in vitro[J];Acta Academiae Medicinae Militaris Tertiae;2005-21
8 DONG Xiao-jing 1 , HU Li-na 3 , SUN Cai-xin 2 , ZHU Yun-shan 1 , HONG Chuan 2 , LI Cong 1 , LUO Xiao-dong 1 , MI Yan 2 ( 1 Department of Obstetrics and Gynecology, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010; 2 Key Laboratory of Voltage Engineering and Electrical New Technology, College of Electrical Engineering, Chongqing University, Chongqing 400044, 3Department of Obsterics and Gynecology, Huaxi Second Hospital, Sichuan University, Chengdu 610041, China);Dosage and safety evaluation of energy controllable steep pulse in treatment of implanted rabbit tumors[J];Acta Academiae Medicinae Militaris Tertiae;2007-03
9 WU Xiao-juan1, YAO Zhen-wei1,TANG Jun-ying1, YAO Chen-guo2, SUN Cai-xin2 (1Department of Gynecology and Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016; 2 Key Laboratory of High Voltage and Electrical New Technology of Ministry of Education, College of Electrical Engineering, Chongqing University, Chongqing 400044, China);Growth inhibition and apoptosis induction of nanosecond steep pulse on human ovarian carcinoma cell line SKOV_3[J];Acta Academiae Medicinae Militaris Tertiae;2007-17
10 Zhou Wei1,Xiong Zheng'ai1,Liu Ying1,Li Chengxiang2,Yao Chenguo2(1Department of Gynecology and Obstetrics,Second Affiliated Hospital,Chongqing Medical University,Chongqing,400010;2State Key Laboratory of Power Transmission Equipment and System Security and New Technology,Chongqing University,Chongqing,400030,China);Apoptosis and necrosis of HeLa cells induced by irreversible electroporation[J];Acta Academiae Medicinae Militaris Tertiae;2010-18
【Secondary References】
Chinese Journal Full-text Database 3 Hits
1 Zhou Wei1,Xiong Zheng'ai1,Liu Ying2,Zhang Qin1,Li Chengxiang3,Yao Chenguo3(1Department of Gynecology and Obstetrics,Second Affiliated Hospital,Chongqing Medical University,Chongqing,400010;2Department of Gynecology and Obstetrics,First Affiliated Hospital,Chongqing Medical University,Chongqing,400016;3State Key Laboratory of Power Transmission Equipment and System Security and New Technology,Chongqing University,Chongqing,400030,China);Effect of sublethal dosage of pulse electric fields on malignant biological behavior of HeLa cells[J];Journal of Third Military Medical University;2012-16
2 LING Xiao-juan1,ZHANG Chen-ling1,XIONG Zheng-ai2,LI Cheng-xiang3,YAO Chen-guo3(1.Department of Gynaecology and Obstetrics,Baoji Central Hospital,Baoji 721008,Shanxi,China;2.Department of Gynaecology and Obstetrics,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010;3.The Key Laboratory of High Voltage and Electrical New Technology,Ministry of Educ,Chongqing University,Chongqing 400044,China);Study on dose of steep pulsed electric fields in rabbit liver[J];Biomedical Engineering and Clinical Medicine;2010-02
3 YANG Xiao-yan1,XIONG Zheng-ai1,LI Cheng-xiang2,YAO Chen-guo2,SUN Cai-xin2,WU Jing1,ZHAO Dong-yang21.Department of Gynecology and Obstetrics,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China;2.Key Laboratory of High Voltage Engineering and Electrical New Technology of Ministry of Education,Chongqing University,Chongqing 400044,China;Research of Irreversible Electrical Breakdown of Steep Pulse in the Treatment of Rabbit Liver Cancer[J];Journal of Southwest University(Natural Science Edition);2009-04
【Secondary Citations】
Chinese Journal Full-text Database 8 Hits
1 MI Yan 1, SUN Cai? xin 1, YAO Chen? guo 1, XIONG Lan 1, HU Ya 2, HU Li? na 2 (1. The Key Laboratory of High Voltage Engineering and Electrical New Technology, Ministry of Education, Chongqing University, Chongqing 400044, China; 2. The Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China);Development and Application of Steep Pulse Apparatus for Tumor Treatment[J];Journal of Chongqing University(Natural Science Edition);2003-02
2 Zhang Jin-zhu Kong Ke-jian (Dept. of Cell Biophysics Institute of Biophysics, Academia Sinica.) Lu Qi-wu Dong Ren-jie (Technical Center of Analyses and Measurements Institute of Biophysica, Academia Sinica.);FREEZE-FRACTURING STUDIES ON HUMAN ERYTHROCYTE MEMBRANES EFFECTED BY EXTERNAL PULSED ELECTRICAL FIELD[J];Acta Biologiae Experimentalis Sinica;1994-02
3 SUN Cai-xin 1 , YAO Chen-guo 1 , XIONG Lan 1 , MI Yan 1 , LIAO Rui-jin 1 , HU Li-na 2 , HU Ya 2 (1.Key Laboratory of High Voltage Engineering and Electrical New Technology,Ministry of Education,Chongqing 400044,China;2.Second Affiliated Hospital,Chongqing University of Medical Science,Chongqing 400010,China);KILLING EFFECTS OF PULSED ELECTRIC FIELDS ON MALIGNANT TUMOR CELL[J];Acta Biophysica Sinica;2002-04
4 Yao Chenguo 1 Sun Caixin 1 Mi Yan 1 Xiong Lan 1 Hu Lina 2 1(Key Lab of High Voltage Engineering and Electrical New Technology, Chongqing University, Chongqing 400044, China) 2(Second Affiliated Hospital,Chongqing University of Medical Science, Chongqing 400010, China);Development of Energy-controllable Steep Pulse Apparatus for Tumor Treatment[J];Chinese Journal of Scientific Instrument;2003-06
5 Yu Tinghe,Peng Mingli,Wang Zhibiao Institute of Ultrasound Engineering in Medicine,Chongqing Medical University Chongqing 400016;A Stereological Study on the Mitochondria in Ovarian Carcinoma Cells Damaged by Ultrasound[J];CHINESE JOURNAL OF ULTRASOUND IN MEDICINE;2000-04
6 LI Da - qiang,et al (Department of Obstetrics and Gynecology, Second College of Clinical Medicine, Chongqing Medical University);Observation of injuring effect of energy controllable steep pulses on tumor tissues cut from the hosts ' body[J];Acta Universitatis Scientiae Medicinae;2001-04
7 Niu Zhong-qi(Xidian University,Xi'an);THE SELF-ELECTRIC FIELD STRESS EXERTED ON CELL MEMBRANE[J];CHINESE JOURNAL OF BIOMEDICAL ENGINEERING;1994-01
8 Zhu Fansan;Chen Baihao;Lin Jiarui;Xie Zeping(Huazhong University of Science & Technology,Wuhan);EXPERIMENTAL STUDIES OF R-WAVE SYNCHRONIEINGELECTRIC PULSES TREATMENT FOR CANCER[J];CHINESE JOURNAL OF BIOMEDICAL ENGINEERING;1995-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved