Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Acta Academiae Medicinae Militaris Tertiae》 2007-04
Add to Favorite Get Latest Update

Proteomic analysis of lymph nodes affected by esophageal squamous cell carcinoma by two-dimensional gel electrophoresis

WANG Bin 1,LI Jun-cai 2,FU Zhong-xue 2,ZHU Dan 3(1Department of Cardiothoracic Surgery, 2Department of General Surgery,The First Affiliated Hospital, 3Laboratory of Clinical Diagnostics,Chongqing Medical University,Chongqing 400016,China)  
Objective To analyze the differential expression of proteome between metastatic lymph nodes and normal lymph nodes in esophageal squamous cell carcinoma.Methods Two dimensional polyacrylamide gel electrophoresis(2-DE)technique and computer-assisted image analysis were used to separate the protein spots and analyze the differential expression of proteome in the metastatic lymph nodes and normal lymph nodes.Results There were 23 protein spots significantly differentially expressed,of which 4 protein spots were newly found,1 protein spot disappeared,14 protein spots increased markedly,and 4 protein spots decreased significantly.Conclusion The proteomic expression in metastatic lymph nodes of esophageal squamous cell carcinoma is significantly different from that of the normal lymph nodes,which may be associated with the mechanism of metastasis of esophageal squamous cell carcinoma.
【Fund】: 重庆市自然科学基金(2006BB5302)~~
【CateGory Index】: R735.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 2 Hits
1 MA Hui wen, LIANG Hou jie (Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Relationship between expression of vascular endothelial growth factor receptor 3 and lymphangiogenesis in esophageal carcinoma[J];Acta Academiae Medicinae Militaris Tertiae;2004-17
2 QIU Xuefeng, PAN Tiecheng, LI Jun, CHEN Tao, WEI Xiang, SONG Ding-wei, HU Ming, ZHANG Li. (Department of Thoracic and Cardiac Surgery, Tongji Hospital, Tongji Medical College , Huazhong University of Science and Technology , Wuhan 430030,China);The study on detection of micrometastasis in lymph nodes and its prognostic significance in patients with PN_0 esophageal carcinoma[J];Tumor;2005-04
【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 Tao Wenhu Yu Zaicheng Department of Thoracic Surgery,The First Affiliated Hospital of Anhui Medical University,Hefei,230022,China;Development of lymphangiogenesis research in esophageal carcinoma[J];Oncology Progress;2006-02
2 WANG Bina,LI Jun-caib,FU Zhong-xueb,DONG Pu-jiangb,HUANG Kai-shunc(a.Department of Cardiothoracic Surgery,b.Department of General Surgery,The First Affiliated Hospital,c.Institute of Basic Medicine,Chongqing Medical University,Chongqing 400016, P.R.China);Proteomic analysis of esophageal squamous cell carcinoma cells between carcinoma tissue and metastatic lymph nodes[J];Journal of Chongqing University;2008-05
3 LU Pei1,LU Huiqi2,HAN Huanxing2,ZHU Xueyuan1,HUANG Qiufang1,GONG Wei1.(1.Department of Clinical Laboratory,the Eighth People′s Hospital,Shanghai 200235,China;2.Department of Laboratory Diagnostics,Changzheng Hospital,the Second Military Medical University,Shanghai 200003,China);Detection of VEGF-C and VEGFR-3 gene expression in esophageal carcinoma by real-time fluorescent quantitative method[J];Laboratory Medicine;2009-05
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CUI YA-nan1,BO Li-hua1,XUE Li-juan2,YANG Shao-juan1,BU Li-sha1,GAO Shen1(1.Central Laboratory,China-Japan Union Hospital,Jilin University,Changchun,130033,China;2.Department of Organ Transplantation Center, First Hospital,Jilin University,Changchun 130021,China);Effects of 5-Fu on apoptosis of human colon cancer cells and expressions of related genes[J];Journal of Jilin University(Medicine Edition);2007-01
2 Su Xu,Zhang Yingchtun,Liu Jianxiang,et al(Radiobilogy research Unit,Ministry of Public Health);Effects of in vitro culture of murine thymocytes on their apoptosis and cell cycle progression[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1995-05
3 MA Hui wen, LIANG Hou jie (Department of Oncology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Relationship between expression of vascular endothelial growth factor receptor 3 and lymphangiogenesis in esophageal carcinoma[J];Acta Academiae Medicinae Militaris Tertiae;2004-17
4 HUANG Wen bin reviewing , ZHOU Xiao jun checking (Department of Pathology, Nanjing General Hospital of Nanjing Command/Clinical School of Medical College of Nanjing University, Nanjing 210002, Jiangsu, China);Proteomics research in defecting tumors of digestive system[J];Journal of Medical Postgraduates;2004-05
5 HUANG Wen-bin,ZHANG Li-hua,CHEN Jie-yu,ZHOU Xiao-jun(Department of Pathology,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing 210002,Jiangsu,China);Preliminary analysis of two-dimensional gel electrophoresis maps in gastric carcinoma[J];Journal of Medical Postgraduates;2007-09
6 LI Xiao bin, FANG Ding zhu, LIN Yi, et al. Department of cardiac and cerebral surgery Taihe hospital, Yunyang Medical college, Hubei 442000;Clinical Signification of DNA Content and Cell Cycle Analysis in Human Esophageal Carcinoma[J];Chinese Clinical Oncology;2003-03
7 Long Xiaoying, Zhu Min, Li Zhiqiang (Department of Pharmacy, Pharmaceutical College of Guangdong, Guangzhou 510224);Effect of Dioscora bulbiferea L. rhiizoma , a traditional Chinese medicine on pharmacokinetics of doxorubicin[J];CHINESE JOURNAL OF CLINICAL PHARMACY;2000-02
8 CHEN Zhi-zhong (School of Pharmacy, Fudan University);Progress on Studies of Anticancer Principles in Natural Drugs[J];Chinese Journal of Ethnomedicine and Ethnopharmacy;2004-05
9 DENG You-Lin 1) , ZHU Wen ** , ZHOU Qing-Hua *, WANG Yan-Ping, CHEN Xiao-He,LIU Lun-Xu,CHE Guo-Wei (Key Laboratory of Lung Cancer Molecular Biology, West China Hospital, Sichuan University, Chengdu 610041, China);Two-Dimensional Gel Electrophoresis of Human High-Metastatic Large Cell Lung Cancer Cell Lines Before and After Transfection of nm23-H1 Gene[J];Chinese Journal of Biochemistry and Molecular Biology;2005-05
10 Guo Fuzheng Qiu Shulan Xiao Xueyuan He Dacheng (Institute of Cell Biology, College of Life Science; Beijing Normal University, Beijing, 100875);LCM laser capture microdissection technology and its applications[J];Modern Instruments;2003-01
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Feng Yumei Li Shuling Li Xi et al Cancer Hospital&Institute,Tianj in Med ical University,Tianjin;Detection of the Micrometastases in Peripheral Blood of Patients with Bre ast Cancer by Means of Reverse Transcriptase-Polymererase Chain Reaction for Cytocreatin 19 Free of Pseudogene Interference[J];Chinese Journal of Clinical Oncology;2003-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved