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《Journal of Third Military Medical University》 2012-01
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Correlation of serum PSA with Gleason score and pathological stage after radical prostatectomy in patients with prostate cancer

Lu Zhiyong1,2,Wu Zhihui3,Wu Xiaohou1(1Department of Urology,First Affiliated Hospital,Chongqing Medical University,Chongqing,400016;2Department of Urology,Affiliated Hospital of Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,750004;3Division of Urology,Department of Surgery,Prince of Wales Hospital,The Chinese University of Hong Kong,Hong Kong,999077,China)  
Objective To investigate the correlation of serum prostate specific antigen(PSA) with Gleason score and pathological stage after radical prostatectomy in patients with prostate cancer.Methods A survey has been performed on 100 inpatients with prostate cancer who underwent robot-assisted laparoscopic radical prostatectomy(rLRP) using the da Vinci robotic surgical system from Jan 2008 to Sep 2010 in the surgery department,urology division of the Prince of Wales Hospital at The Chinese University of Hong Kong.Spearman rank correlation was applied to evaluate the correlation of serum total PSA with Gleason score and pathological stage after radical prostatectomy.Results Serum total PSA was significantly positively correlated with Gleason score(r=0.382,P0.01),but not significantly correlated with pathological stage(r=-0.073,P0.05).Conclusion Serum total PSA is correlated with Gleason score but not correlated with pathological stage after radical prostatectomy in patients with prostate cancer.
【CateGory Index】: R737.25
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