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《Journal of Third Military Medical University》 2012-01
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Correlation of serum PSA with Gleason score and pathological stage after radical prostatectomy in patients with prostate cancer

Lu Zhiyong1,2,Wu Zhihui3,Wu Xiaohou1(1Department of Urology,First Affiliated Hospital,Chongqing Medical University,Chongqing,400016;2Department of Urology,Affiliated Hospital of Ningxia Medical University,Yinchuan,Ningxia Hui Autonomous Region,750004;3Division of Urology,Department of Surgery,Prince of Wales Hospital,The Chinese University of Hong Kong,Hong Kong,999077,China)  
Objective To investigate the correlation of serum prostate specific antigen(PSA) with Gleason score and pathological stage after radical prostatectomy in patients with prostate cancer.Methods A survey has been performed on 100 inpatients with prostate cancer who underwent robot-assisted laparoscopic radical prostatectomy(rLRP) using the da Vinci robotic surgical system from Jan 2008 to Sep 2010 in the surgery department,urology division of the Prince of Wales Hospital at The Chinese University of Hong Kong.Spearman rank correlation was applied to evaluate the correlation of serum total PSA with Gleason score and pathological stage after radical prostatectomy.Results Serum total PSA was significantly positively correlated with Gleason score(r=0.382,P0.01),but not significantly correlated with pathological stage(r=-0.073,P0.05).Conclusion Serum total PSA is correlated with Gleason score but not correlated with pathological stage after radical prostatectomy in patients with prostate cancer.
【CateGory Index】: R737.25
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【Citations】
Chinese Journal Full-text Database 3 Hits
1 HU Wang-Ping1, FENG Fu-ying1, YE Gui-yun2, XIAO Shao-lin3, ZHANG Hong-bin1, WANG Hai-lin1, ZHENG Miao1 (1Department of Clinical Chemistry, General Hospital of Fuzhou Command of PLA, 3 Department of Medical Laboratory, Jianxin Hospital of Fujian Province, Fuzhou 350025; 2Department of Medical Laboratory, First Hospital of Nanping, Nanping 353000, China);Serum complexed-PSA and ratio of complexed/total PSA to improve diagnostic specificity on identifying prostate cancer[J];Acta Academiae Medicinae Militaris Tertiae;2007-18
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1 YANG Jun-fu,ZHANG Hui,WU Yu-dong,ZHAO Ya-bing,LIANG Hong(Department of Urinary Surgery,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China);Expression of nucleostemin gene in prostate cancer and its correlation with prostate specific antigen[J];Acta Academiae Medicinae Militaris Tertiae;2008-03
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3 TANG Qing-lai1,YAO Mao-yin2,XUE Jun3,HUI Ji-hong1,LIU Fa-de1(1.Department of Urology,the Affiliated Jiangning Hospital of Nanjing Medical University,Nanjing 211100,China;2.Department of Urology,Zhongda Hospital,Southeast University,Nanjing 210009,China;3.Department of Urology,Second Affiliated Hospital of Nanjing Medicial University,Nanjing 210011,China);Expression of prostate specific membrane antigen and prostate specific antigen in prostatic adenocarcinoma tissue and its correlation with clinical stages of prostatic adenocarcinoma[J];Journal of Southeast University(Medical Science Edition);2010-01
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1 LIU Heliang 1 WANG He 1 ZHANG Geng 1 QIN Weijun 1 CHEN Baoqi 1 QIN Rongliang 1 YUAN Jianlin 1 SHAO Guoxing 1 ( 1Department of Urology,Xijing Hospital,Fourth Military Medical University,Xi'an, 710032,China);The relationships among clinical stage, pathological grade, PSA level in patients with prostate cancer[J];Journal of Clinaical Urology;2002-12
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