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《Journal of Third Military Medical University》 2012-01
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Executive function of adolescents with conduct disorder:a control study

Zou Zhili,Meng Huaqing,Li Jing,Hu Hua,Ma Zhongrui,Du Lian(Mental Health Center,First Affiliated Hospital,Chongqing Medical University,Chongqing,400016,China)  
Objective To study the correlation between conduct disorder and executive function of adolescents using Cambridge neuropsychological test automated battery(CANTAB).Methods A control study was performed in 86 adolescents with conduct disorder and 118 normal controls using Wechsler adult intelligence scale short form(WAIS-S),intra/extra dimensional set shift(IED),stockings of Cambridge(SoC) and spatial working memory(SWM) in CANTAB.Results The intelligence quotient(IQ) of adolescents with conduct disorder was lower than that of normal controls(98.17±5.07 vs 103.42±5.40,P0.01).IED showed that the number of pre-ED errors,EDS errors,and total errors was greater in adolescents with conduct disorder than in normal controls(12.23±9.15,16.69±10.57 and 35.44±11.09 vs 8.31±3.80,13.07±10.31 and 25.63±12.24,P0.01) while the number of stage-solved problems was less in adolescents with conduct disorder than in normal controls(7.47±1.96 vs 8.29±0.91,P0.05).SOC demonstrated that the minimum moves to solve problems were significantly more in adolescents with conduct disorder than in normal controls(7.65±1.96 vs 6.70±2.05,P0.01).The mean moves(3 and 5) to solve problems were significantly more while the starting time to consider the 4 and 5 moves was shorter in adolescents with conduct disorder than in normal controls(P0.05).SWM displayed that the number of errors found in 6 and 8 boxes was greater and the strategy score was higher in adolescents with conduct disorder than in normal controls(27.56±18.88 vs 20.47±18.40,33.84±4.58 vs 32.00±5.05,P0.01).Conclusion Adolescents with conduct disorder have certain defects in executive function.
【Fund】: 重庆市教育委员会科学技术研究项目(KJ080322)~~
【CateGory Index】: R749.9
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