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《Journal of Third Military Medical University》 2012-19
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Treatment of early esophageal cancer with endoscopic mucosal resection using a ligation device

Peng Guiyong,Chen Lei,Long Qingling,Zhao Jinjin,Peng Zhihong,Dai Jianhua,He Tianhu,Zhou Qian(Institute of Gastroenterology,Southwest Hospital,Third Military Medical University,Chongqing,400038,China)  
Objective To study the value of endoscopic mucosal resection using a ligation device(EMRL) for early esophageal cancer and precancerous lesions.Methods Sixty-six patients with early esophageal cancer underwent EMRL for early esophageal mucosal cancer and moderate-severe atypical esophageal hyperplasia in Digestive Endoscopic Center of Southwest Hospital from January 2010 to April 2012.The nature and area of superficial esophageal lesion were assayed with Lugol's solution staining.The invasion depth of esophageal cancer was assessed by endoscopic typing.The lesion was removed by marking its area with APC,placing a variceal ligation device on a dual-channel endoscope,connecting an operating device to a channel,and inserting a high frequency electrocoagulation ligation device through another channel.The procedure time and incidence of complications and relapse were observed and recorded.Results Of the 66 patients with superficial esophageal mucosal lesion,31 were diagnosed with esophageal intra-mucosal squamous cell carcinoma and 35 were diagnosed with moderate-severe atypical esophageal mucosal hyperplasia.The maximal diameter of esophageal cancer was 1-6 cm.The time of EMRL was 5-55 min(mean 21 min).Significant bleeding occurred during operation and stopped after electrocoagulation hemostasis.No perforation and delayed bleeding occurred after operation.The patients were followed up for 1-26 months during which no recurrence of esophageal cancer was observed.Conclusion EMRL is an effective procedure for esophageal mucosal cancer and precancerous lesions when its indications are strictly controlled.
【Fund】: 重庆市科技攻关项目(2008AC5003)~~
【CateGory Index】: R735.1
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【Co-references】
Chinese Journal Full-text Database 2 Hits
1 WU Yu-wei,PENG Gui-yong,LONG Qing-lin,CHEN Lei,LI Xiang-hong (Gastroenterology Research Institute,Southwest Hospital,Third Military Medical University,Chongqing 400038,China);Ultrasonic endoscopy in differentiating intramucosal carcinoma from submucosal carcinoma in the upper gastrointestinal tract[J];Acta Academiae Medicinae Militaris Tertiae;2009-16
2 ZHANG Lei HAO Chang-qing ZHAO De-li ZHOU Rui-xue JI Peng ZHANG Xiao-hua HE Shun ZHANG Yue-ming YU Gui-xiang JU Feng-huan CHENG Rong-rong XUN Hua-ying WANG Gui-qi 1.Department of Endoscopy of Beijing Cancer Hospital Chinese Academy of Medical Sciences 100021 2.Cancer Hospital of Linzhou in Henan Province 3.People' s Hospital of Feicheng in Shandong Province;Minimal Invasive Treatment of Early Esophageal Cancer and its Precancerous Lesion:Endoscopic Mucosal Resecti[J];Digestive Disease and Endoscopy;2007-01
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