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《Chinese Journal of Control of Endemic Disenaces》 2002-01
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Analysis of relationship between level of arsenic in drinking water and some skin affections

WANG Lian-fang,WANG Sheng-ling, LIN Qin,et al Xinjiang Institute for Endemic Disease Control and Research,Urumqi,830002  
Objective To study the relation between the level of arsenic in drinking water and some skin affections, which included arsenic keratosis, pigmentation and depigmentation on trunk caused from arsenic, semitransparent keratosis spots on palms, nonspecific depigmentation spots, sporadic brown spots and small red spots on trunk, etc.Methods Skin affections of inhabitants were examimed in the area investigated, and analysed the relation of the rate of each skin affection with the level of arsenic in drinking water, respectively.Results All of three diagnosis indexes i.e.arsenic keratosis, pigmentation and depigamentation on trunk only found in arsenism area, and had significantly positive correlation with the level of arsenic in drinking water.No positive correlation relationship between the level of arsenic of drinking water and these mild affections included semi-transparent keratosis spots on palms, nonspecific depigmentation spots and small red spots on runk were found, and these affections could find in those inhabitants living in the area had lower level of arsenic in drinking water. The affection of sporadic brown spots on trunk was also found in the people in all units investigated, but it had an obvious positive correlation with arsenic level in drinking water in the unit had not improvement water. Conclusions These results showed that three arsenism diagnosis indexes i.e. arsenic keratosis, pigmentation and depigmention are specific affection for arsenism but those nonspecific affections such as semi-transparent keratosis spots, nonspecific depigmentation spots, and red spots on trunk, etc. are not specific affections for arsenism.
【Fund】: 中国自然科学基金资助项目 (39860 0 7) ;; 新疆科技厅项目 (980 1 0 30 0 8)
【CateGory Index】: R599.9
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