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《Chinese Journal of Control of Endemic Disease》 2002-06
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Effects of supplying iodine on TSH-receptor antibody in inhabitants with iodi ne deficiency

GUO Xiao-wei(Shandong Institute for Endemic Disease Control and Research,Jinan 250014)  
Objective To study the effects of supplying iodine on thyroid auto immunity in iodine deficiency bodies.Methods The levels of serum TRAb and TSAb w ere tested by ELISA after administrating oral iodized capsule.Results The levels of TRAb and TSAb after supplying iodine were much higher than those before supp lying iodine.The ratio of positive TRAb was increased markedly,high up to 24.4% twelve months later.Conclusions Supplying iodine for the individuals with iodine deficiency may raise the levels of autoantibodies,and increase the positive rat e.It indicates that supplying iodine for the individuals with iodine deficiency might be prone to induce thyroid autoimmune reaction,with a tendency to develop AITD.
【Fund】: 山东省卫生厅资助项目(1995CA1DK1)
【CateGory Index】: R581.3
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Chinese Journal Full-text Database 10 Hits
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