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《Chinese Journal of Control of Endemic Diseases》 2012-03
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X-rays manifestation of bones lesion and changes after improving water to reduce fluoride for children endemic skeletal fluorosis

HUANG Chang-qing The First Institute of Prevention and Treatment on Endemic Diseases of Jilin Province,Baicheng 137000,China  
Objective To konw x-rays manifestation and features of bone lesion of children endemic skeletal fluorosis and similarities and differences between adults and children and changes after improving water to reduce fluoride so as to provide references for diagnosis,evaluation of control effect and mechanism of occurrence and outcome of children endemic skeletal fluorosis.Methods 30 cases of children endemic skeletal fluorosis were screened by x-rays methods in endemic fluorosis areas where fluoride level in drinking water was high(4.3 to16.0 mg/L).The patients' various kinds of x-rays signs and characteristics were observed and analysed.Tracing observation and analysis of x-rays manifestation and diagnosis of 8 children skeletal fluorosis were conducted and compared from pre-water improvement to post-water improvement.Results In 30 cases of children endemic skeletal fluorosis,the mild,the moderate and the severe were followed by 22 cases,4 sases and 4 cases.Among the patients,osteosclerosis-type,osteomalacia-type and mix-type were followed by 26 cases,2 cases,2 cases.An abnormal bone trabecula x-rays sign was overwhelming in all 30 patients,which appeared as bone trabecula increased in number,densety,thickness,ambiguity,structural disorder and fusion.Serious bone trabecula structural disorder and fusion caused bone mineral density increased,osteosclerosis and softening and deformation of the skeletal of forearm,shank and pelvis.Different from adult fluorosis,the joints and soft tissue surrounding bones were ont abnormal.Conclusions Children endemic skeletal fluorosis occurs mainly in areas with higher fluorosis level in drinking water.X-rays manifestations showed a damage on sclerotin,jionts and soft tissue surrounding bones were not affected.5 years after improving water to reduce fluoride,original abnormal skeletal x-rays signs were markedly reversed or returned to normal.The patients of osteosclerosis before improving water appeared osteoporotic signs after improving water,whose mechanism needs further study.
【CateGory Index】: R725.9
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【Citations】
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【Co-citations】
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