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《Chinese Journal of Control of Endemic Diseases》 2014-01
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The results of urinary iodine monitoring are affected by the urine collected in different period of time

CHEN Zhi-hui;WU Jia-ni;LAN Ying;Fujian Center for Disease Control and Prevention;  
Objective To explore that the urine collected from 8-10-year-old children in different period of time had an influence on the median urinary iodine in population. Methods Chosen the typical coastal and mountainous areas. Collected 7 batches urine from the school-age children in coastal area at 8: 30,9: 30,10: 30,11: 30, 14: 30,15: 30 and 16: 30. Collected 4 batches urine from the school-age children in mountainous area at 8: 30,10: 30, 14: 30,and 15: 30. The urinary iodine level was determined by arsenic cerium catalytic spectrophotometry. The urinary specific gravity was determined by ATAGO UG-α digital refractometer. Results Significant difference of the median urinary iodine of the 7 batches urine which were collected from the school-age children in coastal area was observed( Z = 62. 129, P = 0. 000). The median urinary iodine of the any batche urine which were collected in the afternoon was significantly higher than the median urinary iodine of the any batche urine which were collected in the morning. No significant difference of the median urinary iodine of the 4 batches urine which were collected from the school-age children in mountainous area was observed( Z = 7. 740, P = 0. 052). There was a positive correlation between the urinary iodine level of the school-age children and their urinary specific gravity, the correlation coefficients were 0. 5 ~ 0. 8,all P = 0. 000. Conclusion There is a difference of the urinary iodine level of the school-age children between the morning urine and the afternoon urine. So we suggest that the time we collect the urine should be clear in the monitoring scheme. At the same time, we should pay attention to the urine specific gravity which affect on the urine iodine value in individual.
【Fund】: 卫生部委托项目(卫办疾控函【2012】19号)
【CateGory Index】: R446.12
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