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《Chinese Journal of Control of Endemic Diseases》 2014-S1
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A clinical observation on oral administration of YinChenSiLingTang combined with large doses of Danshen injection for treatment of patients with severe hepatitis

ZENG Xiang-jin;LUO Yun;MA Lin-jian;PENG Lei;  
Objective to observe the clinical therapeutic effect of oral administration of YinChenSiLingTang combined with large doses of Danshen injection for treatment of patients with severe hepatitis.Methods 38 patients with severe hepatitis hospitalized the hospital of Integrated Chinese and Western Medicine of Dazhou Sichuan Dazhou were randomly divided into treatment group(18 cases)and control group(20 cases).The patients in control group were treated with conventional medical treatment and Plasma exchange.(PE),while the patients in treatment group were treated with YinChenSiLingTang 1 times per day combined with large doses of Danshen injection 80ml intravenous infusion twice daily on the basis of treat ment in the control group.the therapeutic course was 28 days in both groups,The changes of clinical symptoms and Blood routine,liver function,blood coagulation function in both groups were observed after 28 days of treatment.Results:The mortality in treatment group was significantly lower than that in the control group after 28 days of follow-up(P0.01),the degrees of abdominal distention fatigue,mouth bitterness improved obviously compared with those in the control group(P0.05).The white blood cell count(WBC),red blood cell count(RBC),hemoglobin(Hb),blood ammonia,TBIL in the two groups were markedly decreased and prothrombin activity(PTA)in creased after treatmen,there were statistical significant differences in WBC、RBC、TBiL 、PTA 、PLT bet ween the two groups(P0.05).Conclusion:Oral dministration of YinChenSiLingTang combined with large doses of Danshen injection is an effective proposal which can improve the hypercholesterolemia,reduce the course of the illness and decrease mortality in patients with severe hepatitis.
【CateGory Index】: R575.1
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