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《Chinese Journal of Control of Endemic Diseases》 2014-S1
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Clinical observation of valsartan combined with amlodipine in the treatment of type 2 diabetes mellitus complicated with hypertension

LI Xin-xin;  
Objective To investigate the clinical efficacy of valsartan combined with amlodipine besylate in treatment of type 2 diabetes mellitus complicated with hypertension.Methods 150 cases of hypertensive patients with type 2 diabetes,randomly divided into amlodipine besylate group,valsartan group and combined group,50 cases in each group.Amlodipine besylate group received 5mg/d of amlodipine besylate,valsartan group received valsartan 80mg/d,combined group received valsartan 80mg/d and 5mg/d of amlodipine besylate.8 weeks for 1 course of treatment and three groups of clinical curative effect were compared.Results The total effective rate in combination group was significantly higher than the other two groups.SBP and DBP in combined group decreased more obviously.Urinary albumin excretion rate was significantly lower than the other two groups.Conclusion Amlodipine combined with valsartan in the treatment of type 2 diabetes with hypertension had significant efficacy and less adverse reaction.It could significantly reduce the damage of target organs and be worthy of promotion.
【CateGory Index】: R544.1
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