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《Chinese Journal of Control of Endemic Diseases》 2014-S1
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Clinical observation of valsartan combined with amlodipine in the treatment of type 2 diabetes mellitus complicated with hypertension

LI Xin-xin;  
Objective To investigate the clinical efficacy of valsartan combined with amlodipine besylate in treatment of type 2 diabetes mellitus complicated with hypertension.Methods 150 cases of hypertensive patients with type 2 diabetes,randomly divided into amlodipine besylate group,valsartan group and combined group,50 cases in each group.Amlodipine besylate group received 5mg/d of amlodipine besylate,valsartan group received valsartan 80mg/d,combined group received valsartan 80mg/d and 5mg/d of amlodipine besylate.8 weeks for 1 course of treatment and three groups of clinical curative effect were compared.Results The total effective rate in combination group was significantly higher than the other two groups.SBP and DBP in combined group decreased more obviously.Urinary albumin excretion rate was significantly lower than the other two groups.Conclusion Amlodipine combined with valsartan in the treatment of type 2 diabetes with hypertension had significant efficacy and less adverse reaction.It could significantly reduce the damage of target organs and be worthy of promotion.
【CateGory Index】: R544.1
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 Gu Ye(Xiezhuang Coal Mine Hospital of Shandong Xinwen Mining Group Company,Department of Pharmacy,Xintai 271221,China);Clinical Effect of Combine Using Valsartan and Amlodipine in Treatment of Hypertension with Type 2 Diabetes[J];Chinese Journal of Medicinal Guide;2012-08
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【Co-citations】
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1 Yuan Jing-ping;Department of Cardiology Jiaxing Hospital of Traditional Chinese Medicine of Zhejiang Province;;Efficacy and Safety of Valsartan/hydrochlorothiazide in Treatment of Mild and Moderate Essential Hypertension[J];Chinese Journal of Medicinal Guide;2014-02
2 SHEN Qingqing;ZENG Mingyong;ZHAO Yuanhui;College of Food Science and Engineering,Ocean University of China;;Modification of Acaudina Molpadioides Hydrolysates by Plastein Reaction and Preparation of ACE Inhibitory Peptides[J];Chemical Journal of Chinese Universities;2014-05
3 QIU Tian-lin;WANG Xia;YUAN Jun;WANG Geng;WANG Min;The NO.2 People's Hospital of Deyang,Department of Pharmacy;The NO.2 People's Hospital of Deyang,Department of internal medicine;;Observation on the Clinical Effect of Safflower Yellow Pigment Injection in the Adjuvant Ttreatment of Early Diabetic Nephropathy[J];Progress in Modern Biomedicine;2013-30
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1 LI Pei-lin1, YANG Rui1, ZHOU Yong2, CHEN Hong1, CAI De-hong1 1Department of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China; 2Mingjing Hospital, Foshan 528300, China;Clinical significance of glycosylated serum protein in patients with diabetic nephropathy[J];Journal of Southern Medical University;2011-06
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