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Clinical Analysis of Thrombin Combined with Octreotide in Treatment of Hepatocirrhosis Complicated with Upper Gastrointestinal Bleeding

Jiang Zhiping;Hubei Provincial People's Hospital;  
Objective the study was designed to analyze the clinical effect of thrombin combined with octreotide in treatment of hepatocirrhosis complicated with upper gastrointestinal bleeding.Methods 74 cases of liver cirrhosis combined with upper gastrointestinal bleeding patients receiving treatment in our hospital from September,2015 to September,2016 were selected as the sample,and they were randomly divided into two groups--experimental group and control group with 37 cases in each.The control group was applied conventional treatment methods combined with octreotide treatment;the experimental group, based on the conventional treatment methods,was applied thrombin combined with octreotide treatment. Observation of the two groups was made on patients' conditions while being hospitalized and treated, duration of symptom improvement,adverse reactions,and treatment effect.Results the experimental group, with patients' hospitalization time of(6.9 + 5) d,blood transfusion volume(231.6 + 50.1) ml, time of hemostasis(20.6 + 3.7) h,duration of symptom improvement(1.91 + 0.02) d,rate of adverse reaction probability 2.70%,the total efficiency of treatment 97.3%,showed significant advantage comparing with the control group.Conclusion thrombin combined with octreotide should be utilized in clinical treatment of hepatocirrhosis complicated with upper gastrointestinal bleeding.
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