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《Progress In Veterinary Medicine》 2001-04
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Preliminary Research on the Preparation of the Fast Dissolving Tablets of Ribavirin

LUO Yan hong 1, HUANG Zong hai *, ZHAO Xiao nong 2, LIAN Xiu juan 3, ZHANG Yong de * (1.College of Animal Science and Veterinary Medicine, Northwest Science and Technology University of Agriculture and Forestry,Yangling,Shaanxi,712100,Chin  
The fast dissolving tablets of Ribavirin were prepared by using adjuvants of microcrystalline cellulose and starch. In order to determine the appropriate process and formulation, an orthogonal experiment design L8(2 7) was used with the index of disintegrated time .Scanning the Ribavirin between the wavelength 200~400 nm with ultraviolet spectrophotometer,the λmax was 207 nm. Standard curve of Ribavirin was drawn out , Regression equation was A= 2.25×10 -3 +0.043C ,r=0.9994. The average recovery was 99.51%,and RSD=0.89%.Quality examination of the fast dissolving tablets of Ribavirin indicated that the content uniformity of Ribavirin tablets accorded with the standard of《 Chinese Pharmacopoeia》 2000 edition.
【CateGory Index】: S859.79
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