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《Progress in Veterinary Medicine》 2017-02
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Progress on Regulation Mechanism of Pancreatic Embryonic Development and Differentiation of Stem Cells

YANG Pei-lin;L Hao;ZHAO Dong-dong;LIN Shu-mei;Institute of Animal Husbandry and Veterinary Medicine,Shenyang Agricultural University;  
At present,the incidence of diabetes has increased year by year,how to control and prevent diabetes is becoming a worldwide subject.The traditional treatment method can not only solve the problem of hyperglycaemia,but also can not control the diabetic complications effectively.Although the technologies of islet transplantation provide a new way,the deficiency of the islets and the immune rejection in islet transplantation have restricted the development of islet transplantation.Therefore,it has become a new technique to repair the pancreatic tissue by the differentiation of pancreatic stem cells(PSCs)and achieve stable blood glucose and control the diabetic complications.In this paper,the development regulation mechanism of pancreatic embryos,the localization of pancreatic stem cells and the methods of inducing differentitation in vitro were reviewed.
【Fund】: 国家自然科学基金项目(31572481)
【CateGory Index】: R587.1
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