Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Progress in Veterinary Medicine》 2017-02
Add to Favorite Get Latest Update

CYP3A Enzyme and Its Potential Significance in Metabolic Properties of Bactrian Camels

YUE Wei-dong;SAN Ren;HASI Su-rong;College of Veterinary Medicine,Inner Mongolia Agricultural University;Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease,Ministry of Agriculture;  
Cytochrome P4503A(cytochrome P4503 A,CYP3A)is the most important functional form of the CYP enzyme superfamily in animal liver,account for 30% of the total hepatic CYP enzymes,and responsible for biotrans formation of 45%-60% commonly used drugs in vivo.The systematic study on various CYP3 Aenzymes was carried out,including the molecular structure,genetic diversity,in vivo activity of CYP3 A,and the influencing factors.We reviewed the biological characteristics of the CYP3 Asubfamily,the significance of CYP3 Aenzyme in the metabolism of endogenous compounds and xenobiotics,CYP3 Agene expression and regulation,induction and inhibition of the CYP3 Aenzyme,and research achievements of Bactrian camel CYP3 Aenzyme in this article.
【Fund】: 国家自然科学基金项目(31260623)
【CateGory Index】: S852.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 6 Hits
1 WANG Yan;GAO Fei;HASI Surong;College of Veterinary Medicine,Inner Mongolia Agricultural University,Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease,Ministry of Agriculture;Inner Mongolia Institute of Camel Research;;Establishment and Optimization of Incubation System of Bactrian Camel Studying CYP2D6 Enzyme in Vitro[J];动物医学进展;2016-04
2 PEI Le;ZHANG Wen-bin;Hasisurong;College of Veterinary Medicine, Inner Mongolia Agricultural University/Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture;Bactrian Camel Institute of Alashan,Inner Mongolia;Inner Mongolia Institute of Camel Research;;Determination of the Activities of Bactrian Camel CYP3A Enzyme by Specific Probe Drug[J];中国农业科学;2015-16
3 HASI Su-rong;LI Qing;YU Siri-guleng;JIRI Mu-tu;Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease of Ministry of Agriculture,College of Veterinary Medicine,Inner Mongolia Agricultural University;College of Food Science and Engineering,Inner Mongolia Agricultural University;;Comparative Study of CYP Gene Family in Bactrian Camel(Camelus bactrianus)[J];畜牧兽医学报;2015-07
4 ZHANG Li-qun;BA La;YUSI Riguleng;HASI Surong;College of Veterinary Medicine,Inner Mongolia Agricultural University;Alsha Camel Science Institute;;Advance in Cytochrome P450 2J Subfamily[J];动物医学进展;2014-08
5 ZHOU Tao;WANG Yu-guang;MA Zeng-chun;XIAO Yong;TANG Xiang-lin;LIANG Qian-de;HU Dong-hua;XIAO Cheng-rong;TAN Hong-ling;GAO Yue;School of Pharmacy,Guangxi Medical University;Institute of Radiation Medicine,Academy of Military Medical Sciences;;Ginkgolide B induces CYP3A4 expression through activation of human pregnane X receptor[J];中国药理学通报;2014-07
6 CHEN Jie,ZHAO Li-zi,DENG Ying,WANG Xue-ding,GUAN Su,HUANG Min.Institute of Clinical Pharmacology,School of Pharmaceutical Sciences,Sun Yat-Sen University,Guangzhou,Guangdong 510080,China Corresponding author:HUANG Min,Institute of Clinical Pharmacology,School of Pharmaceutical Sciences,Sun Yat-Sen University,Guangzhou,Guangdong 510080,China;Small interfering RNA mediated silencing of cytochrome P450 3A4 gene[J];中国基层医药;2006-04
【Co-citations】
Chinese Journal Full-text Database 9 Hits
1 MAO Yuanyuan;ZHENG Rongquan;ZHANG Qipeng;MEI Yiyun;KONG Shenshen;LIU Zhifang;College of Chemistry and Life Sciences, Zhejiang Normal University;Key Lab of Wildlife Biotechnology and Conservation and Utilization of Zhejiang Province;Xingzhi College, Zhejiang Normal University;;Transcriptome sequencing analysis on pearl color related genes in Hyriopsis cumingii[J];水产学报;2018-03
2 WU Xiao-hua;ZHANG Li;ZHU Lei;DAI Ya-ping;Department of Pharmacy,First People's Hospital of Wujiang District,Suzhou;Jiangsu Institute of Food and Drug Supervision and Inspection;;Effects of tetramethylpyrazine on drug metabolizing enzyme CYP3A4 in HepG2 cells and its mechanism[J];实用药物与临床;2017-11
3 YUE Weidong;Bala;Sanren;Hasisurong;College of Veterinary Medicine, Inner Mongolia Agricultural University, Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Diseases, Ministry of Agriculture;Bactrian Camel Institute of Alshaa;Inner Mongolia Institute of Camel Research;;Determination on plasma concentrations of midazolam in Bactrian camels by HPLC[J];畜牧与兽医;2017-10
4 NING Chen-qing;MENG Qiang;LIU Ke-xin;Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University;;Role of hepatic transporters and metabolic enzymes in chemical substancesinduced liver injury[J];药物评价研究;2017-09
5 YANG Jiao;CAO Chang-e;LAI Yong;DU Yi-min;GAO Yang-yang;DONG Yu;College of Pharmacy and Chemistry,Dali University;Affiliated Hospital of Dali University;;Effect of breviscapine on CYP3A4 and CYP2C19 activities and its molecular mechanisms in Chang Liver cells[J];中国医院药学杂志;2017-16
6 SAN Ren;BA La;YUE Wei-dong;HASI Su-rong;Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease,Ministry of Agriculture,College of Veterinary Medicine,Inner Mongolia Agricultural University;Camel Institute of Alshan;Inner Mongolia Institute of Camel Research;;Determination of Acetaminophen in Bactrian Camel Plasma by RP-HPLC[J];中国畜牧兽医;2017-08
7 ZHANG Feng-jing;GU Zheng-biao;LI Zhao-feng;HONG Yan;CHENG Li;LI Cai-ming;School of Food Science and Technology,Jiangnan University;The State Key Laboratory of Food Science and Technology,Jiangnan University;Collaborative Innovation Center for Food Safety and Quality Control of Jiangsu Province;;Effects of different drying methods on the quality of ginkgo powder[J];食品工业科技;2017-09
8 YU Xi;WAN Zi-jin;ZHU Yan-ping;XU Hai-rong;LIAO Kai;LIU Feng;LI Wei;College of Medicine,Yangzhou University;Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases;;Investigation of inductive effect of triptolide on cytochrome P450s in rat hepatocytes and HepG2 cells and possible mechanism[J];中国药理学通报;2017-03
9 YUE Wei-dong;SAN Ren;HASI Su-rong;College of Veterinary Medicine,Inner Mongolia Agricultural University;Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease,Ministry of Agriculture;;CYP3A Enzyme and Its Potential Significance in Metabolic Properties of Bactrian Camels[J];动物医学进展;2017-02
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 PEI Le;ZHANG Wen-bin;Hasisurong;College of Veterinary Medicine, Inner Mongolia Agricultural University/Key Laboratory of Clinical Diagnosis and Treatment Technology in Animal Disease, Ministry of Agriculture;Bactrian Camel Institute of Alashan,Inner Mongolia;Inner Mongolia Institute of Camel Research;;Determination of the Activities of Bactrian Camel CYP3A Enzyme by Specific Probe Drug[J];中国农业科学;2015-16
2 XUE Yadong;WU Sanxiong;SUN Zhicheng;GUO Tiezheng;SHALA Hanapiya;LI Diqiang;Key Laboratory of Forest Ecology and Environment of State Forestry Administration,Institute of Forest Ecology,Environment and Protection,Chinese Academy of Forestry;Administrative Bureau of Gansu Dunhuang Wetland National Nature Reserve;Administrative Bureau of Xinjiang Lop Nur Wild Camel National Nature Reserve;;Research and Conservation of Wild Camel: Present Status and Future Prospects[J];四川动物;2014-03
3 LIU Chun 1,2,WU Liu-cheng 2,WANG Sheng-jie 2,SHAO Yi-xiang 2(1.College of Veterinary Medicine,Yangzhou University,Yangzhou,Jiangsu,225009,China;2.Laboratory Animal Center,Nantong University,Nantong,Jiangsu,226001,China);Effect of Three Different Coccidiostats on Expression of CYP1A2 mRNA and Protein in Rabbits[J];动物医学进展;2013-07
4 XIA Zong-ling,CHEN Rong,WANG Ming-li*(Third Affiliated Hospital of Suzhou University,Department of Pharmacy Changzhou 213000,China);Establishment and Verification of Cytochrome P450 3A Enzyme Induction Model in Female Rats[J];中国药学杂志;2013-12
5 LIU Rong-Rei,LIU Xing,LIU Xiao-Yu,FAN Wen-Ting,ZHAO Dong-Dong,SHI Wang-Rong,ZHU Yu-Tian,LI Hong(College of Food science and Technology,Huazhong Agricultural University,Wuhan 430070,China);Identification of Metabolites and Pathway in Liver Microsomes of Phoxim in Crucian Carp by High Performance Liquid Chromatography and Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry[J];分析化学;2013-06
6 XIE Min-Min,GONG Da-Ping,LI Feng-Xia,LIU Guan-Shan,SUN Yu-He Key Laboratory of Tobacco Genetic Improvement and Biotechnology,Chinese Academy of Agricultural Sciences,Tobacco Research Institute,Chinese Academy of Agricultural Sciences,Qingdao 266101,China;Genome-wide analysis of cytochrome P450 monooxygenase genes in the tobacco[J];遗传;2013-03
7 QIU Xiang-jun1,WANG Zhe2, XU Tao2,LUO Shun-bin2, HU Guo-xin2 (1.Medical College of Henan University of Science and Technology,Luoyang 471003,Henan Province,China;2.School of Pharmacy of Wenzhou Medical College,Wenzhou 325027,Zhejiang Province,China);Determination of the activity of CYP3A in rat liver microsomes by HPLC[J];中国临床药理学杂志;2012-11
8 WANG Yu-lin,WANG Shao-xia,GUO Hong,HU Li-min(Insitute of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine,Tianjin 300193,China);Regulatory mechanisms of P-glycoprotein at the blood-brain barrier[J];中国药理学通报;2011-09
9 XU Yuying,ZHANG Yin,ZHOU Fan,ZHENG Yifan,ZHU Xinqiang(Institute of Nutrition and Food Safety,Zhejiang University,Hangzhou 310058,China);Human pregnane X receptor-mediated transcriptional regulation of CYP3A4 by extracts of 7 traditional Chinese medicines[J];中国中药杂志;2011-11
10 Jian Tunyu~1,Xu Fan~2,Liao Chunlong~3,Xu Guili~2(1.The First Clinical College of Kunming Medical University,Kunming General Hospital of Chengdu Military Region,Kunming 650032,China;2.Kunming General Hospital of Chengdu Military Region;3.Dali University);Comparison of Three Methods for Determining Rat Liver Microsomal Protein Content[J];中国药师;2011-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved