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《Progress in Veterinary Medicine》 2017-12
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Effects of High-concentrate Diet on Blood Biochemical Parameters and Hepatic Lipid Metabolism in Lactating Dairy Goats

MA Ju-hong;LEI Qi-jing;NI Ying-dong;LI Xian;YIN Yu-peng;LI Guo-hong;HU Xiao-hong;ZHANG Yan;CHEN Shu-lin;CONG Ri-hua;College of Veterinary Medicine,Northwest A&F University;College of Veterinary Medicine,Nanjing Agricultural University;Chenggu County Animal Husbandry and Veterinary station;Institute of Animial Husbandry,Hannan Agricultural Academy;  
The purpose of this study was to explore the effect of long-term feeding of high-concentrate diets on the formation mechanism of milk and provide a theoretical basis for scientific breeding of lactating dairy goats.In this study,14 early-lactation Guanzhong dairy goats were selected and randomly divided into two groups:the control group was fed 35% concentrate of dry matter,and fed 65% concentrate of dry matter as the experimental group.The experiment lasted for 19 weeks.Compared with the control group,the concentration of glutamic-pyruvic transaminase was up-regulated significantly(P0.05)and triglyceride has a tendency to decrease in blood of dairy goats fed high-concentrate diets.In the experimental group,the hepatic cells showed swelling degeneration or vacuolar degeneration.However,there was no significant difference in the lipid metabolism and anabolism related gene expression between the experimental group and the control group.The results of this study showed that long-term feeding of high-concentrate diets can lead to increased blood glutamic-pyruvic transaminase,suggesting that this may be related to liver cell damage,but the expressions of genes related to lipid metabolism were not significantly changed.
【Fund】: 陕西省农业科技攻关项目(K3310215109);; 陕西省自然科学基金项目(2016JM3033);; 海南省重大科技计划项目(ZDKJ2016017)
【CateGory Index】: S827.5
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