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《Progress in Veterinary Medicine》 2017-12
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Effects of He-Ne Laser Combined with Salvia Miltiorrhiza on Immune Indices of Rheumatoid Arthritis Rats

HAO Jin-qi;CHEN Xia;LU Gai-ling;JI Jing-jing;YU Yan-qin;ZHOU Yun;Baotou Medical College;  
To study the changes of organ coefficient,immune indices and inflammatory factors in the model of collagen induced rheumatoid arthritis in rats by Salvia miltiorrhiza combined with laser for providing a new therapy for the treatment of rheumatoid arthritis,the rats were injected with the chicken collagen of typeⅡfor inducing rats rheumatoid arthritis model,and then divided randomly into 5 groups.The changes of organ coefficients,immune indices,rheumatoid factor and inflammatory factors(IL-6,IL-1)were measured.IgA level in serum of rat group with Salvia miltiorrhiza plus laser was higher than that in the model group and other treatment groups(P0.05),IgG and IgM levels of Salvia miltiorrhiza combined with laser group was lower than that of model group and other treatment groups(P0.05).Compared with the model group and the blank control group,the organ coefficients of the rats in each treatment group decreased(P0.05).The contents of IL-1,IL-6 and RF in serum of treatment group were lower than that in model group,and higher than that in control group(P0.05).It can be seen that Salvia miltiorrhiza combined with laser has a certain degree of therapeutic effect on type II collagen induced rheumatoid arthritis rat model.
【Fund】: 包头市医药卫生科技计划项目(Wsjj2014014)
【CateGory Index】: R-332;R593.22
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