Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Progress in Veterinary Medicine》 2017-12
Add to Favorite Get Latest Update

Progress on lncRNAs in Organ Fibrosis

DING Hai-mai;LI Cai-yan;ZHANG Xue-ming;Department of Biochemistry and Molecular Biology,Baotou Medical College;School of Pharmacy,Bao tou Medical College;  
Organ fibrosis is acute or chronic pathological lesions caused by various of factors,which seriously affectshumanhealth.long noncoding RNAs are non-protein coding transcripts longer than 200 nucleotides.Increasing evidence revealed that lncRNAs have key functions in regulating diverse disease processeses,such as chromatin modification,transcription,post-transcription.lncRNAsareinvolvedintheregulation of fibrosis processes,which are expected to become molecular markers of the organ fibrosis diagnosis,prognosis and drug new targets.This article reviewed progress in lncRNAs source,mechanism of action and the latest research on organ fibrosis for providing insights into the clinical diagnosis and lncRNAs as a drug target in the treatment of organ fibrosis.
【Fund】: 内蒙古自然科学基金项目(2016MS(LH)0306)
【CateGory Index】: R363
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved