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《Progress in Veterinary Medicine》 2018-06
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Progress on Factors Influencing Fitness Cost Caused by Antibiotic Resistance in Bacteria

YANG Xiao-qing;LIN Si-tong;SUN Lei;ZHANG De-xian;LIU Ming-chun;College of Animal Husbandry and Veterinary Medicine,Shenyang Agricultural University;  
Most antibiotic resistance can confer a fitness cost that is typically observed as a reduced bacterial growth rate.The fitness cost of resistance will allow susceptible bacteria to outcompete resistant bacteria if the selective pressure from antibiotics is reduced.The fitness cost is the main factor that influence the development of resistance,which means the resistance might decrease if antibiotic uses were reduced.Unfortunately,the available data suggest that the resistance is still in developing,and no sign indicates that reversibility is emerging because of measures whichhavebeentaken.Inthisreview,we reviewed the factors that influence the fitness cost of antibiotic resistance,which will be beneficial in preventing the development of antibiotic resistance.
【Fund】: 辽宁省教育厅科学研究一般项目(LSNYB201601)
【CateGory Index】: S852.61
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