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《Journal of Chinese Electron Microscopy Society》 2002-01
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Ultrastructural observation of bronchial amyloidosis

ZHU Mei fang 1,YI Xiang hua 1,ZHANG Rong xuan 1,ZHONG Ci sheng 2,MA Qian li 1,KONG Jie 1 (1 Department of Pathology, Shanghai Pulmonary Hospital, Shanghai 200433,China; 2 Electron Microscopy Laboratory, Fudan University Medical School, Shan  
The amyloid specimen taken during the patient operation from bronchia in one case of amyloidosis was observed under the light microscope and electron microscope. Under the electron microscope it was found that amyloid deposited extracellularly in a macular shape with pale grey colour. The amyloid deposit was composed of fine filament like substance of 5~10nm in diameter in irregular array. There were lots of active fibroblasts and macrophages around the deposit. In the cytoplasm of the surronding,well developed Golgi complex and rich rough endoplasmic reticulum can be seen. The endoplasmic reticulum was expanded and full of grey fine filament like substance, whose shape was similar to the amyloid outside the cell. It is suggested that the amyloid substance may be produced by fibroblasts. The macrophages contained many phagosomes. In some of the phagosomes grey macular substance, which had the shape similar to the extracellular phagocytic plaque, was found. This findings suggest that macrophages might clear off parts of the amyloid substance.
【CateGory Index】: R562
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【Co-references】
Chinese Journal Full-text Database 1 Hits
1 BAI Mei~1,SHANG Yan~2,TANG Zhi-hong~3 (1.No.253 of Hospital,Huhhot 010050,China; 2.Shanghai Changhai Hospital,Shanghai 200000,China; 3.Tongliao City Hospital,Tongliao 028000,China);Primary Tracheobronchial Amyloidosis 10 Cases Treated with Bronchoscopy Nd:YAG[J];Journal of Inner Mongolia University for Nationalities(Natural Sciences,Quarterly);2004-05
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