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《肺癌杂志》 1998-01
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Determination of Iodine~(125) labelled monoclonal ras oncoprotein in plasma from non smoking female lung cancer patients and healthy controls

Zhu Lifang, Cheng Jiarong,Li Hongnian et al. Shanghai Cancer Institute, Shanghai 200032, P.R.China  
Objective To explore the significance of oncoprotein in plasma in the carcinogenic process of lung cancer. Methods ras oncoprotein in plasma was assayed in 38 lung cancer patients and 59 healthy women for controls among non smoking females by Western Blot analysis with monoclonal ras antibody as the primary antibody and iodine 125 labelled technique.Results Positive samples were found in 35 of the 38 patients versus 17 of the 59 controls, odds ratio(OR) was 28.8(χ 2 MH =36.85). OR for 35 positive samples with 23(+),8(),4() was 21.5 , 112.0 and 56.0 respectively (χ 2 MH =27.45,30.58 and 19.70). ras oncoprotein levels of the plasma from the lung cancer patients were statistically significantly higher than those from the controls(P 0.001 ). Conclusion An increasing of ras oncoprotein in plasma could be a possible biomarker of epidemiologic study for female lung cancer. ras oncoprotein may be used to health surveillance of high risk population due to environmental and occupational exposure.
【CateGory Index】: R734.2
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 Wan Da-fang;Li Hong-nian;Zhang Ping-ping et al Shanghai Cancer Institute, Shanghai;EXPRESSION OF ONCOGENE PRODUCTS INFEMALE LUNG CANCER TISSUES[J];Tumor;1990-05
2 Zhong Li-jie; Gao Yu-tang; Jin Fan,et al.(Shanghai Cancer Institute, Shanghai 200032);The ASSOCIATION OF COOKING AIR POLLUTION ANDLUNG CANCER RISK:RESULTS FROM A CASE-CONTROLSTUDY IN NONSMOKING WOMEN IN SHANGHAI[J];TUMOR;1995-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Zhi-hong,LIU Hong-mei,LIU Ting,LI Hai-jun (Departement of Preventive Medicine,Ningxia Medical College,Yinchuan 750004 China);Effects of Siritch Vapor Condensate on Lipid Peroxidation and Cu,Zn,Fe,and Ca in Mice[J];Industrial Health and Occupational Diseases;2005-02
2 Li Dongyang,Xie Hongwei,Rang Weiqing,et al.the Department of Hygiene,Hengyang Medical College,421001;Effects of Cooking Oil Fume on the Lipid Peroxidation and Levels of Zinc,Copper and Iron in Lung Tissue and Serum Among Rats During Different Exposure Periods[J];JOURNAL OF ENVIRONMENT AND HEALTH;1999-06
3 LIU Xiu_fang, LIU Gui_zhu, KOU Hua_wei,et al Department of Hygenic Toxicology, Ningxia Medical College, Yinchuan 750004;Effects of Siritch Vapor Condensate on Lipid Peroxidation and Mutagenicity in Mice[J];Journal of Environment and Health;2002-02
4 FENG Shui-dong,LING Hong-yan,CHEN Feng.School of Public Heath,Nanhua University,Hengyang,Hu nan421001,China;Meta Analysis of Female Lung Cancer Associated With Cooking Oil Fume[J];Journal of Environment and Health;2003-06
5 FENG Shui-dong, CHEN Feng. Department of Epidemiology, School of Public Health, Nanhua Uinivercity, Hengyang, Hunan 421001, China;Progress of Epidemiology Study on Cooking Oil Fume Toxicity[J];Journal of Environment and Health;2004-02
6 HUANG Bo,CHEN Feng,ZHU Mao-xiang,et al.Public Health College of Nan Hua University,Hengyang,Hunan 421001,China;Antagonism of DMSO against Genotoxicity of Cooking Oil Fume Condensate to BEAS-2B Cell[J];Journal of Environment and Health;2007-03
7 RANG Wei-qing,ZHOU Shao-qin,SU Qi, et al (Department of Hygiene,Hengyang Medical College,Hengyang, Hunan 421001,China);Experimental Study on Expression of P~(53) Gene of Lung Tissues in Rats Exposed to COF[J];Journal of Hengyang Medical College;2000-06
8 LONG Ying,HUANG Bo,LI Dong-yang,et al(Public Health College of Nanhua University,Hengyang,Hunan 421001,China);Study on Frequency of HPRT Locus Mutation in Human Bronchial Epithelial Cells Induced by COFC[J];Journal of Nanhua University(Medical Edition);2007-02
9 WANG Jiu-chen,DONG Ren-jie;The influence of the comprehensive rural energy construction on indoor air quality in western rural area[J];Renewable Energy;2005-05
10 ZHANG Hui 1,WANG Guo xiong 1,XIANG Long sheng 1,ZHAO Li 2,TANG Zhen 2,ZHANG Jing 1,SUN Ya hui 1 (1.Department of Environmental Health,School of Public Health, Southeast University,Nanjing 210009,China; 2.Sanitary and Anti epidemic Station,Xu;Investigation on the T and B Lymphocyte Subtypes in Peripheral Blood of Cooking Workers[J];Journal of Nanjing Railway Medical College;2001-01
China Proceedings of conference Full-text Database 1 Hits
1 Zhang Hui, Wang Guoxiong, Shen Chuanlai, Xiang Longsheng, et al. (Department of Environmental Health, Public Health School, South east University, Nanjing 210009);Investigation on the Immunological Index for Cell-mediated Immunity in Cooking Workers[A];[C];2005
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Xu Lai Jin Libin Wan Dafang Li XiuzhenLi Hongnian Gu Jianren(Department of Biochemistry and Molecular Biology, Shanghai Cancer Institute);CONSTRUCTION OF v-ki-ras EXPRESSION PLASMID[J];Chinese Journal of Virology;1987-03
2 Qu Young-hua;THE MUTAGENICITY OF PRODUCTS FROM HEATED OIL IN AMES TEST[J];Tumor;1986-02
3 Wu Yi-qian et al, Shanghai Cancer Institute, Shanghai;~(32)P-POST LABELING ANALYSIS OF RAPESEED OIL CONDENSATE-DNA ADDUCT FORMATION[J];Tumor;1992-06
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