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Value of pulmonary diffusion capacity in predicting the short term prognosis after lung resection in lung cancer patients

Gu Yueqing, Zhou Yunzhong, Chen Jialu, et al. Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai 200030, P.R.China  
Objective To determine the relationship between pulmonary diffusion capacity (D LCO) and the short term prognosis after lung resection in patients with lung cancer. Methods A retrospective analysis of 413 consecutive patients with lung cancer who underwent lung resection was performed. Among them, 27 had low D LCO before operation (D LCO60% predicted for total pneumonectomy or bilobectomy, 50% predicted for lobectomy), as a low D LCO (LD LCO) group,and other 386 patients as a control group.Results There were more patients with chronic bronchitis, history of heavy smoking and underwent chemotherapy or radiotherapy preoperatively in LD LCO group than those in control group. The hospital mortality rates within 30 days after lung resection were no significant difference between the two groups (P0.05),whereas incidence of respiratory complications in LD LCO group was higher than that in control group (P0.05). Conclusion A reduction in D LCO before operation can remarkably increase respiratory complications after pulmonary resection. D LCO is one of important predictors of risk for lung resection.
【CateGory Index】: R734.2
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