Clinical significance of detection of IL-2R for non small cell lung cancer
Tian Hui *,Cao Bingzhen,Wang Shanzheng. *Department of Thoracic Surgery,The Affiliated Hospital of Shandong Medical University,Jinan 250012,P.R.China
Objective To explore the clinical significance of SIL 2R of serum and IL 2R expression of cancer tissue in non small cell lung cancer. Methods SIL 2R levels in the serum and IL 2R expression in cancer tissues were detected in 42 non small cell lung cancer by ELISA and immunohistochemistry respectively.Results Serum SIL 2R level was significantly higher in lung cancer group than that in normal control group (P0.05) , and significantly higher in stage Ⅲ,Ⅳ disease than that in stage Ⅰ,Ⅱ disease (P0.05), but it was not associated with histological classification of the cancer (P0.05).IL 2R expression was significantly higher in lung cancer tissue than that in normal lung tissue (P0.05) and was significantly higher in stage Ⅲ,Ⅳ cancer than that in stage Ⅰ,Ⅱ cancer (P0.05). But it was not related to cancer types (P0.05) .Conclusion The results suggest that detection of serum SIL 2R and IL 2R expression of the cancer tissue might be useful to predict stages of cancer and monitor the prognosis of patients with lung cancer.
【CateGory Index】： R734.2