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《Journal of Abdominal Surgery》 2018-04
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Risk factors of parapyloric lymph nodes metastasis in Siewert type Ⅱ esophagogastric junction adenocarcinoma

Li Ming;Meng Qingbin;Shao Yongsheng;Li Dongliang;Feng Yan;Wu Wenliang;Lu Xin;Huangyang;Department of Gastrointestinal Surgery,Xishui Country People's Hospital of Hubei Province;  
Objective To investigate the risk factors of parapyloric lymph nodes metastasis in Siewert type Ⅱ esophagogastric junction adenocarcinoma.Methods The clinicopathological data of 85 patients with Siewert type Ⅱesophagogastric junction adenocarcinomas who underwent radical surgery during January 2013 to December 2017 were retrospectively analyzed.The number of lymph nodes in each case was recorded.The total and average number and the metastasis ratios were calculated.The risk factors were analyzed.Results 4 167 lymph nodes in 85 Siewert type Ⅱ esophagogastric junction adenocarcinomas were detected in surgical specimens and the average number was 49.02±16.24.68 in85 cases having lymph node metastasis and the overall lymph node and PLN metastasis rate was80.00% and 18.82% respectively.The PLN metastasis was not related to gender,age,tumor differentiation,type and Laurén type(P0.05),and related to the tumor size and depth of invasion(χ~2=17.358,P0.001;χ~2=14.921,P=0.002).Conclusions The total gastrotectomy should be performed in Siewert type Ⅱ esophagogastric junction adenocarcinomas,especially in cases of T3,T4 stage and the tumor diameter≥4 cm.
【Fund】: 湖北省自然科学基金(2016CFB595);; 湖北省卫生计生委科研基金(WJ2015MB137)
【CateGory Index】: R735
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