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《Radiologic Practice》 2003-01
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~(99m)Tc-MIBI mammoscintigraphy in differentiation of nodular lesions of breast and detection of axillary lymph node metastasis from breast cancer

CHEN Jing,WU Hua,HU Jian,et al.Department of Nuclear Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030  
objective:To evaluate the clinical value of 99m Tc MIBI mammoscintigraphy in differentiation of nodular lesions of breast and detection of axillary lymph node metastases from breast cancer.Methods: 99m Tc MIBI breast imaging was performed in 60 patients with unilateral palpable breast masses.The early and delay images were acquired at 10~20 min and 90~120 min after injection of the tracer.The acquisition included three positions:anterior supine,left and right lateral prone.The ratio of T/NT was calculated as radioactivity of mass to that of oppositive corresponding tissue.The results were compared to pathological findings in all subjects.Results:With 99m Tc MIBI mammoscintigraphy to differentiate nodular lesion of breast,the diagnostic sensitivity and specificity were 92.9% and 90.6% respectively,positive and negative predictive value were 89.7% and 93.5% respectively,and the accuracy was 91.7%.And the sensitivity,specificity,positive predictive value,negative predictive value and accuracy of 99m Tc MIBI mammoscintigraphy for axillary lymph node metastases were 83.3%,86.1%,80%,88.6% and 85% respectively.Conclusion:It is suggested that 99m Tc MIBI mammoscintigraphy may be valuable in differentiating nodular lesions of breast and detecting axillary lymph node metastasis from breast cancer.
【CateGory Index】: R817.4
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