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《Radiologic Practice》 2010-01
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Application Study of MR 3-dimensional Volumetric Interpolated Breath-hold Examination in Whole Liver Perfusion Imaging

LI Yuan-ge.Department of Radiology,Nanshan Hospital,Guangdong 518052,P.R.China  
Objective:To investigate the feasibility and clinical application of 3-dimensional volumetric interpolated breath-hold examination(3D VIBE) in MR whole liver perfusion imaging.Methods:30 healthy volunteers undertook conventional MRI including axial plane with spin echo T1W,T2W,coronal plane with true-FISP and modified 3D-VIBE whole liver perfusion sequences.Selected the regions of interest(ROI) in left hepatic lobe(LHL)、right hepatic lobe(RHL)、abdominal aorta(AO) and portal vein(PV),the signal intensitise of ROIs of different phases and delayed phase after injection of Gd-DTPA were measured respectively,time-concentration curves were drawn.Resules:Four time-concentration curves of LHL、RHL、AO and PV respectively were obtained in each of the volunteers.The dynamic concentration of Gd-DTPA were 0~0.6mmol/l、0~0.6mmol/l、0~1.7mmol/l and 0~1.0mmol/l in LHL、RHL、AO and PV respectively.The time-concentration curve of LHL、RHL and PV were gentle,showing slowly ascended to peak than slowly descended.The time-concentration curves of AO had two peaks which were reached swiftly.Conclusion:It is feasible to use modified 3D-VIBE in whole liver perfusion imaging.Time-concentration curves and quantified perfusion parameters of liver could be obtained,which are very important in estimating the abnormal perfusion of liver.
【CateGory Index】: R575;R445.2
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