Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Radiologic Practice》 2018-01
Add to Favorite Get Latest Update

Imaging and pathology manifestations of primary non-Hodgkin lymphoma of spine

YANG Fan;SUN Peng-fei;NA Man-li;Department of Radiology,Peking University Shougang Hospital;  
Objective:To study the imaging and pathology manifestations of primary nonHodgkin lymphoma(NHL)of spine.Methods:The imaging materials of twelve patients with pathology confirmed primary NHL of spine were retrospectively analyzed.All of the twelve patients had plain CT,of them,9 patients had contrast-enhanced CT.Eleven patients had plain MRI,ten cases with contrast-enhancement.Pathology diagnosis was obtained in 2 patients with surgical resection and 10 patients with needle biopsy.Results:Of the twelve patients,seven cases had solitary vertebral involvement,including cervical spine(one case),thoracic spine(four cases)and lumbar spine(two cases).Five patients had multiple vertebral involvement,with skipped lesions in two cases and contiguous lesions in four cases(one case one case had also skipped lesions).Associated pathology fracture of vertebrae were found in six cases;four cases had collapsed vertebra.CT showed osteolytic lesion with soft tissue mass in nine cases,including seven cases with moth-eaten appearance and two cases with infiltrative bone destruction;mixed osteolytic and osteosclerosis in one case.On MRI,soft tissue mass surrounding vertebrae destruction could be revealed,appearing as low signal on T1WI,high signal on T2WI.The soft tissue mass showed mild-to-moderate enhancement after contrast administration on CT and MRI.The pathology diagnosis was NHL in these 12 patients,with ten cases as diffuse larger B-cell lymphomas(10/12).Conclusion:The imaging findings of primary NHL of the spine mainly manifested as a single or multiple contiguous vertebral body with osteolytic destruction(moth-eaten,infiltrative destruction or associated with osteosclerosis),extra-dural soft tissue mass surrounding the vertebral lesion,normal intervertebral space,yet without periosteal reaction or calcification.Needle biopsy is an important approach for the early diagnosis of primary NHL.
【CateGory Index】: R730.44;R738.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved