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《Radiologic Practice》 2018-04
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CT pulmonary angiography with low tube voltage and low contrast dose for reducing beam-hardening artifact:the feasibility with the third-generation dual-source CT

YANG Meng;ZHANG Zhang;LI Feng-tan;Department of Radiology,Tianjin Medical University General Hospital;  
Objective:To explore the feasibility of low tube voltage and low contrast dose CT pulmonary angiography(CTPA)using the third-generation dual-source CT and its application value in reducing the beam-hardening artifacts.Methods:Totally 60 patients underwent CTPA.All patients were randomly divided into 2 groups:standard group [90 kV and 30 mL contrast media(CM)]and "double-low" group(70 kV and 20 mL CM).Objective image quality was evaluated by calculating CT attenuation,signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),and beam-hardening artifact index(AI).Subjective image quality was assessed by five-point scale.Radiation dose was also recorded.The parameters of objective and subjective image quality were compared with Wilcoxon rank sum test and independent-sample t-test.AI of different branches of pulmonary artery in each group was compared by one-way ANOVA test.Results:There was no significant difference(CT value,SNR and CNR)between the two groups in objective image quality(P0.05).In "double-low" group,radiation dose was significantly lower than that of standard group(P0.05).The AIs of right pulmonary artery(RPA)and right upper lobe pulmonary artery(RULPA)in standard group were significantly higher than those in "double-low group"(t=5.38,P0.01;t=7.82,P0.01).The AIs of RPA and RULPA were higher than those in other branches in standard group,while no difference was found in "double-low" group.The subjective image quality of " double-low" group was also better than that of standard group(Z=4.33,P0.01;Z=4.53,P0.01).Conclusion:Low tube voltage and low contrast dose CTPA with third-generation CT can obtain satisfactory image quality and reduce the influence of beam-hardening artifacts in right pulmonary artery and right upper lobe pulmonary artery.
【Fund】: 天津市应用基础与前沿技术研究计划重点项目(14JCZDJC57000);; 国家自然科学基金青年科学基金资助项目(81301217)
【CateGory Index】: R543.2;R816.41
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