Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Analytical Science》 2012-01
Add to Favorite Get Latest Update

Study on Preparation and Recognition Characteristics of Nicardipine Molecularly Imprinted Polymer

SU Hong-hui1,FENG Li-xia2,SU Hui-ling3,XIU Rong4(1.Department of Medical Material,General Hospital of Huabei Oil Field Company,Renqiu 062552; 2.Department of Foreign Language,Hebei Medical Univercity,Shijiazhuang 050017; 3.Department of Tumor and Blood,General Hospital of Huabei Oil Field Company,Renqiu 062552; 4.Institute of Pharmacy,Hebei Medical Univercity,Shijiazhuang 050017)  
With nicardipine as template molecule,methacrylic acid as function monomer,a molecularly imprinted polymer(MIP) was prepared by the molecular imprinting technique.The MIP was investigated in equilibrium binding experiment to evaluate its adsorption property and selective recognition.Scatchard analysis showed that the dissociation constant(Kd) was 1.03 mmol/L and the apparent maximum binding capacity(Qmax) was 18.76 μmol/g.It indicated that the MIP had high selectivity and high recognition ability for nicardipine.
【Fund】: 河北省科技厅重点项目(No.07276101D-37)
【CateGory Index】: O631.3
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved