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Research Progress of Quantum Dots-Labeled Aptamer Technology in Analysis and Detection

LI Meng-hua;CHU Xian-feng;DOU Xiao-wen;YANG Mei-hua;KONG Wei-jun;OUYANG Zhen;School of Pharmacy,Jiangsu University;Institute of Medicinal Plant Development,Chinese Academy of Medical Science,Peking Union Medical College;  
Quantum dots(QDs),have been paid more and more attention in biological and chemical fields due to their unique optical properties.With the development of biotechnology,aptamers with the characteristics of high specificity,strong affinity are widely used as the biological probe or biological sensor in the field of analysis and detection.The combination of aptamer with QDs can realize highly sensitive,selective and rapid detection.In this review,the synthesis,modification and coupling of QDs are summed up.The application of QDs-labeled aptamer technology in the biological molecules,pathogenic microbes,cells and mycotoxins are then introduced in detail.Finally,the future development trends of QDs-labeled aptamer technology in the field of analysis and detection are prospected.
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