Full-Text Search:
Home|About CNKI|User Service|中文
Add to Favorite Get Latest Update

The sensitivity and specificity of combination with clinical pulmonary infection score(CPIS),C-reactive protein(CRP) and neutrophile granulocyte(NEU) to predict ventilator associated pneumonia

HUA Xianlong;CHEN Xinyu;LAI Rubiao;Department of Intensive Care Unit,Wengyuan people's hospital;  
Objective To observe the sensitivity and specificity of combination with clinical pulmonary infection score(CPIS),C-reactive protein(CRP) and neutrophile granulocyte(NEU) to predict ventilator associated pneumonia.Methods 29 patients with VAP were as observation group,with VAP in mechanical ventilation patients as control group,using the receiveroperating characteristic curve(ROC) evaluation CPIS,CRP and NEU predict the sensitivity of the VAP and specific degrees.Results The group of patients with VAP CPIS,CRP and NEU were significantly higher than the control group(P=0.023,0.039 and 0.023).CPIS corresponds to the area under the curve(AUC) was 0.669,95% confidence interval(CI) to(0.507,0.507); CRP corresponding AUC 0.643,95% CI(0.487,0.487); NEU corresponding AUC 0.661,95% CI(0.507,0.507).CPIS with NEU both with VAP exist significant correlation(P=0.034,0.043),but the CRP and VAP has no significant differences(P=0.074).When the CPIS values of 7 points,the predict the sensitivity of the VAP(positive) was 89.66%,93.26%; When the CRP values for 14 mg/L,the prediction of VAP sensitivity was 79.31%,87.74%; When the NEU values is 83%,and its prediction of VAP sensitivity was96.55%,91.45%.Conclusion Comprehensive CPIS 7 points,CRP 14 mg/L and NEU 83%,the forecasting can significantly increase the sensitivity of the VAP and specific degrees.
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©CNKI All Rights Reserved