Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Clinical Hepatology》 2003-01
Add to Favorite Get Latest Update

Study on level change of serum type - IV collagen and hyaluranate in chronic liver disease patients.

Ye Yuanhong, Zhang Anzhong. Shan Dong Provincial Hospital 250021  
Objective To study the level change of serum type - Ⅳ collagen (Ⅳ-C) and Hyaluranate (HA) in chronic hepatitis and h'ver cirrhosis patients and their value in diagnosis of liver cirrhosis. Method solid phase - sandwich - enzyme immunoassay was used to recorder the level of Ⅳ -C and HA in 96 chronic HBV hepatitis and liver cirrhosis patients and compared with 20 normal people. Result The serum level of HA and Ⅳ-C was correlated with the degree of hepatic fibrosis. Compared with normal people and mild chronic hepatitis, the level of serum Ⅳ -C and HA in moderate and severe chronic hepatitis and h'ver cirrhosis patients significandy raised (P0.05) .Conclusion The level of serum Ⅳ-C and HA can be used as important diagnostic index in evaluation of the degree of hepatic fibrosis. When they used together, the diagnostic accuracy raised.
【CateGory Index】: R575
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 WEN Qing-hui, WAN De-sheng, LI Feng-ying, ZHANG Xi-jian. Department of Clinical Laboratory, Dongguan People′s Hospital, Dongguan 523018, China;Diagnostic value of combined detection of serum Ⅳ-C, HA and LN concentrations for hepatic fibrosis in chronic hepatic patients[J];Laboratory Medicine and Clinic;2007-06
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 Huang Yuxiang,Xie Rongxing.Guangdong Chaozhou central hospital,Chaozhuo 521000,China;The outcome analysis of hepatitis B with small three positive and the markers test for hepatic fibrosis[J];Fujian Medical Journal;2004-03
2 Zhan Hao,Zhang Yongxue.Department of Nuclear Medicine,Xiehe Hospital,Affiliated to Tongji Medical College of Huazhong University of Science & Techology,Wuhan 430022;Clinical value of type Ⅳ collagen and Laminin in diagnosis of chronic liver disease[J];Radiologic Practice;2001-02
3 Ye Lei(Chinese Medical Hospital of Zhejiang Province, Zhejiang 310006);Correlation between Nonalcoholic Steato Hepatitis and Symptom Types of Chinese Medicine[J];Journal of Beijing University of Traditional Chinese Medicine(Clinical Medicine);2004-02
4 Zhu Xiaodong, Huang Jiefei, Ni Runzhuo, et al (Department of Gastroenterology ,Affiliated Hospital,Nantong Medical College,Nantong 226001);THE VALUE OF SIMULTANEOUS DETERMINATION OF SERUM HYALURONIC ACID, COLLAGEN TYPE Ⅳ ,LAMININ LEVEL AND ALPⅤ TO THE DIAGNOSIS OF LIVER FIBROSIS[J];JOURNAL OF NANTONG MEDICAL;2000-02
【Co-references】
Chinese Journal Full-text Database 4 Hits
1 You Shaoli, Zhao Jingmin, Xin Shaojie, et al . 302 Hospital of PLA Beijing 100039;A study on membrane - type I - matrix metalloproteinase mRNA expression in processes of experimental liver fibrosis and its reversal in rats[J];Infections Disease Information;2001-02
2 ZOU Hai-feng,LIU Yang,XU Hua-feng,et al (Department of Biochemistry and Molecular Biology,Harbin Medical University,Harbin 150086,China);Effect of TIMP-1 in hepatic fibrosis[J];Journal of Harbin Medical University;2005-01
3 LIU Jiang,HE Jianfang,SHI Bainian,et al.Central Hospital,Huzhou,Zhejiang 313000,China;Correlation between MMP-2, TIMP-2 and hepatic fibrosis indices in patients with chronic hepatitis B and cirrhosis[J];Journal of Clinical Internal Medicine;2005-08
4 Zhou WenHong,et al;The relation of levels of serum HA、LN、PCIII、IV-C with pathological diagnosis in hepatic fibrosis[J];Zhejiang Clinical Medical Journal;2003-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved