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《Journal of Clinical Hepatology》 2003-04
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Chnicai epidemiologlc evaluation of serum diagnostic index for liver fibrosis

Shao Hong, Azrguli, Chen Lizia,et al. The College of Public Health, Xinjiang Medical University, Wurumqi, 830054, China  
Objective To evaluate usage value of serum liver fibrosis diagnostic index of HA、LN、PⅢ P and Ⅳ-C in clinic practice. Methods FLISA were used to detect sero-diagnostic index in the groups of chronic hepatitis, hepatic cirrhosis and health control,and the receptor operation curve (POC) was used to make clinical evaluation.Results There were statistical significant differences in every parameters in each groups(FHA-139.9, FLN=52.8, FPⅢP=146.7, FⅣ-c=37.2, P0.01),and which showed hepatic cirrhosisver fibrosisronic hepatitis (q test, P0.01).The index of HA and PⅢP have more specific,but HA、LN and Ⅳ-C have more sensitive. The study show HA is more useful than that of others in diagnostic value of liver fibrosis or hepatic cirrhosis. Conclusion The four parameters can be combined for clinical screening and diagnosis of liver fibrosis.
【CateGory Index】: R575.2
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