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《Polymer Materials Science & Engineering》 2010-02
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The Preparation and Characterization of Protein Imprinting Polymer of Chitosan and Metal Ion Coordination Compound

DING Li-bin, WANG Yi-feng(School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, China)  
A molecular imprinting polymer was formed using bovine serum albumin as "print" molecule, epoxy chloropropane as crosslinker, and the coordination compound of chitosan and metal ion as functional matrix. The morphologies of the molecular imprinting polymer were characterized by environmental scanning electron microscope, and the selective adsorption and separation effect was evaluated by protein adsorption experiment. The analytical results show that the imprinted polymer has good selectivity to bovine serum albumin. The bovine serum albumin adsorption of the molecular imprinting polymer is 21.9 times of the non-imprinted polymer. The imprinted polymer shows good selective adsorption and separation ability to the bovine serum albumin.
【Key Words】： chitosan bovine serum albumin molecular imprinting polymer protein imprinting
【Fund】： 国家自然科学基金面上项目(50703030)
【CateGory Index】： O631.3
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