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《Chinese Journal of Bone and Joint Injury》 2017-08
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Research on characteristics of middle-aged and senile patients with osteonecrosis of femoral head

WANG Zhen-tao;GUO Yue;XIE Bin;WANG Jun-yu;SHEN Dan-qing;LI Yan;CHEN Wei-heng;Guiyang University of Chinese Medicine;  
Objective To investigate the clinical characteristics of middle-aged and senile patients with osteonecrosis of the femoral head(ONFH) in order to guide clinical diagnosis and treatment by reviewing clinical data retrospectively. Methods A total of 1078 ONFH patients in department of orthopedics of our hospital from Jan 2012 to Aug 2016 were selected as research objects. Of which, 302 patients aged over 50 years were regarded as the observation group,while 309 patients aged from 30 to 39 years old were regarded as the control group. The gender, etiology, side, whether there was misdiagnosis,clinical course and the differences in body mass index were compared between the two groups. Results In the observation group,187 patients were 50 to 59 years old and 78 patients 60 to 69 years old,while 37 patients were over 70 years old. In the control group the proportion of men was higher than the observation group, the differences were statistically significant( P 0.05). In comparison, the proportion of patients with idiopathic and trauma in the observed group was higher than that in the control group, while hormones, alcohol, hormones, alcohol and other factors were lower than those in the control group, the differences were statistically significant(P 0.05). The bilateral incidence was 58.6%, compared with 70.6% in the observer group,the differences were statistically significant(P 0.05). The clinical course of the observation group was(25.59 ±5.27)months and was longer than that of the control group(18.09 ±21.69)months,the differences were statistically significant(P 0.05). Conclusion The incidence of middle and senile patients with ONFH has increased continuously. Clinical characteristics are that incidence increases in women and decreases with age, and the clinical course is longer. More attention should be paid to the early diagnosis and prevention of trauma.
【Fund】: 国家自然科学基金面上项目(81373656);; 北京市自然科学基金面上项目(7142170)
【CateGory Index】: R681.8
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