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《International Eye Science》 2019-04
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A Meta-analysis of the efficacy of internal limiting membrane reversal tamponade and internal limiting membrane stripping for macular hole retinal detachment in the highly myopia eyes

Zhi-Hua Huang;Wei Tan;Ying Zhang;Yue-Ling Cui;The Third Affiliated Hospital of Zunyi Medical University,Zunyi Ophthalmology Clinical Medical Center;  
AIM: To evaluate the anatomical and visual recovery effects of vitrectomy( PPV) combined w ith inner limiting membrane( ILM) reversal tamponade or ILM stripping in the treatment of high myopia macular hole retinal detachment( M HRD). METHODS: The literature was retrieved fromChina Know ledge Netw ork( CNKI),VIP,Wanfang Database,PubM ed, EM base, Cochrane Library, European PM C,and Natural database. The search time w as built until September 2018. The 6-month follow-up time w as used to observe the macular hole closure, primary retinal detachment and BCVA. M eta-analysis w as performed using Review 5.3 and Stata 15.1 softw are. RESULTS: In this study,a comparative analysis of 266 eyes in 8 studies w as included. Statistically,the effect of ILM reversal tamponade in the macular hole closure rate is better than ILM stripping, the difference w as statistically significant( RR = 2.05,95% CI 1.69 to 2.49,P0. 00001),there w as no statistically significant difference in the efficacy of primary retinal detachment rate( RR =1. 04,95% CI 0.98 to 1.12,P = 0.21),the BCVA of the tw o groups w as significantly higher than that before surgery at6 mo after surgery, the difference w as statistically significant( RR= 0.44,95% CI 0.33 to 0.55,P0.00001; RR=0.29,95% CI 0. 10 to 0. 48,P = 0. 003). The results of the extent of BCVA improvement betw een the tw o groups are heterogeneous,and the conclusions may be unstable,and more reliable data are needed. CONCLUSION: PPV+ ILM flap insertion is more effective in treating patients w ith high myopia macular hole retinal detachment.
【Fund】: 国家自然科学基金资助项目(No.81660162);; 遵义市创新人才团队培养项目[No.遵市科合(2015)43号];; 贵州省科技计划项目[No.黔科合SY字(2013)3036号]~~
【CateGory Index】: R779.6
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【Citations】
Chinese Journal Full-text Database 5 Hits
1 Liu Haiyun;Sun Xiaodong;Department of Ophthalmology,Shanghai General Hospital of Shanghai Jiao Tong University,Shanghai Key Laboratory of Ocular Fundus Diseases,Shanghai Engineering Center for Visual Science and Photomedicine;;Inverted internal limiting membrane flap technique for macular hole retinal detachment of high myopia[J];中华眼底病杂志;2018-02
2 Huang Zhijian;Chen Xiao;Hong Ling;Yan Ming;Zeng Miao;Department of Ophthalmology,Wuhan General Hospital;;Clinical efficacy of vitrectomy combined with internal limiting membrane tamping on macular hole and retinal detachment in high myopia[J];中华眼底病杂志;2017-04
3 Xu Changzhong;Wu Jianhua;He Junwen;Feng Chao;Aier School of Ophthalmology, Central South University;;Observation of single-layered inverted internal limiting membrane flap technique for macular hole with retinal detachment in high myopia[J];中华眼科杂志;2017-05
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【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 Liu Haiyun;Sun Xiaodong;Department of Ophthalmology,Shanghai General Hospital of Shanghai Jiao Tong University,Shanghai Key Laboratory of Ocular Fundus Diseases,Shanghai Engineering Center for Visual Science and Photomedicine;;Inverted internal limiting membrane flap technique for macular hole retinal detachment of high myopia[J];中华眼底病杂志;2018-02
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【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 Liu Haiyun;Gao Min;Yang Ming;Sun Xiaodong;Shanghai General Hospital,Shanghai Jiaotong University,Shanghai Key Laboratory of Ocular Fundus Diseases,Shanghai Engineering Center for Visual Science and Photomedicine;;Clinical efficacy of vitrectomy combined with modified inverted internal limiting membrane flap covering technique for complicated macular hole[J];中华眼底病杂志;2017-04
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