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《Journal of Clinical Orthopedics and Research》 2018-03
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Reoperation after cervical disc replacement in Chinese mainland population with degenerative cervical disease: A Meta-analysis

Duan Fangfang;Lyu Yanwei;Wang Lifang;Li Donghang;Zeng Cheng;Tian Wei;Department of Spine Surgery,Beijing Jishuitan Hospital;  
Objective To investigate the occurrence of reoperation after artificial cervical disc replacement( ACDR) in Chinese mainland population with degenerative cervical disease. Methods A series of databases including Chinese Biomedical Literature Database( CBM),Chinese Academic Journals Full-Text Database( CNKI),Chinese Science and Technology Journal Database( VIP),Wanfang Database,Pub Med,OVID,Cochrane Library and Embase were searched using "cervical disc replacement"as key words in October2016. The literatures were strictly selected according to inclusion and exclusion criteria. The basic and reoperation related information from literatures that met the criteria were extracted and entered by two independent researchers. The reoperation rate of each study was then merged using the fixed or random effect model of rate Meta-analysis. Results A total of 31 literatures were included in the study,including 8 randomized controlled trials,6 quasi-trials and 17 case-series studies. The reoperation rates of 12,24,36,48,60 and 72 months were 1. 3%( 95% CI: 0. 1%-2. 5%),1. 2%( 95% CI: 0. 3%-2. 2%),1. 0%( 95% CI:-0. 5%-2. 6%),1. 5%( 95% CI:-0. 3%-3. 3%),1. 7%( 95% CI:-0. 3%-4. 1%) and 4. 8 %( 95% CI: 0. 5%-9. 2%),respectively. Conclusion The reoperation rate after ACDR of patients with degenerative cervical disease from Chinese mainland is relatively low. Reoperation are mainly performed in the first year after the CDR and then increased slightly in the 6 th year after the surgery. More long-term monitoring data ware needed in the future.
【Fund】: 国家重点研发计划(2016YFC0105800 2016YFC0105801);; 国家自然科学基金(81400923);; 北京市医院管理局青年人才培养“青苗”计划(QML20150405);北京市医院管理局使命人才培养计划(SML20150401);; 2017北京市优秀人才培养资助(2017000021469G228)~~
【CateGory Index】: R687.3
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