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A Combined Use of fMRI and DTI in Patients with Intracerebral Hemorrhage

YIN Xiao-ping,ZHANG Man-qing,WANG Wei.Department of Neurology,Affiliated Hospital of Jiujiang University,Jiujiang 332001,China  
Objective:To observe the changes of directionality and integrity of neurofibra tracts in patients with intracerebral hemorrhage(ICH)and to explore the relationship between motor dysfunction and integrity of neurofibras Methods:Twenty-one patients with ICH were randomly divided into groups drug and surgery.Injury extent of the corticospinal tracts in patients was detected by Diffusion Tensor Imaging(DTI),and activating extent of the tracts was detected by fMRI in acute and recovery phases.The association of the motor dysfunction in recovery phase with the injury degree of the corticospinal tracts has been analyzed.Results:There was no differences in BI scores of two groups in acute and recovery phases(P=0.2905,P=0.6018).However,there was a significant difference between acute phase and convalescence in each groups(R=0.89862,P=0.0002)by multivariate analysis of variance.The coefficient correlation between the degree of injury of the corticospinal tracts and BI score was 0.764(P=0.0001)in recovery phase.Conclusion:There was correlation between the the recovery of motor function and the integrity of the tracts.The combined use of DTI and fMRI could detect the injury degree of the corticospinal tracts and predicate the prognosis to some extent.
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