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《Neural Injury and Functional Reconstruction》 2014-01
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Clinical Evaluation and Analysis of Risk Facters on Depression and Anxiety in 56 Adult Epilepsy Patients

LIANG Yan-ling;XUE Zheng;KANG Hui-cong;ZHU Sui-qiang;Department of Neurology, Shunde Affiliated First People's Hospital of Southern Medical University;  
Objective:To evaluate the characteristics and the possible risk factors of depression /anxiety in adult epilepsy patients. Methods: The clinical data of 56 adult epilepsy patients have been retrospectively analyzed.HAMD and HAMA were used to assess the depression/anxiety of each patient. In addition, we have analyzed the possible risk factors such as gender, age, educational background, epilepsy onset age, epilepsy history, seizure frequency, seizure type, temporal lobe epilepsy, epilepsy family history, imaging, AEDs, and sports. Results: In the 56 epilepsy patients, the prevalence of depression and anxiety was 26.8%(15 patients) and 30.4%(17 patients) respectively. The most common items were depression mood(93.33%), despair feeling(86.67%),psyche anxiety(30.40%) in HAMD and recognition function(88.24%), intension(82.35%), anxiety mood(76.47%)in HAMA. Gender, on-set age, epilepsy history of the family and sports showed no correlation with with HAMA or HAMD. Both HAMD and HAMA were associated with low schooling, frequent seizures and frontal/temporal lobe abnormality on CT/MR(P 0.05). Age ≥23, epilepsy history ≥9 years,partial seizures, TLE, multiple AEDs treatment were associated with high score of HAMD(P0.05). Conclusion: The proportion of depression or anxiety in adult epilepsy patients are high with various symptoms. Age≥23, epilepsy history ≥9 years,partial seizures, temporal lobe epilepsy or multiple AEDs treatment, low education, frequent seizures or frontal/temporal lobe abnormality on CT/MR are the potential risk factor of depression and anxiety.
【CateGory Index】: R742.1
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