Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Neural Injury and Functional Reconstruction》 2014-01
Add to Favorite Get Latest Update

Application of Magnetic Resonance Imaging in Diagnosis of Multiple System Atrophy

LIN Zhi-jian;CHEN Xu-hui;CHE Xiu-juan;ZHANG Hai-ou;WU Jun;Department of Neurology, Peking University Shenzhen Hospital;  
Objective:To explore the application of magnetic resonance imaging(MRI) in diagnosing multiple system atrophy(MSA) and distinguishing MSA from PD. Methods: Twenty-six consecutive patients with MSA,20 consecutive patients with PD and 18 healthy control subjects were examined with MRI. The imaging changes focused on the presence or absence of brain atrophy including the cerebellum, pons, medulla oblongata and putamen atrophy, cruciform hyperintensity of the pons, slit-like hyperintensity in the posterolateral margin of the putamen, hyperintensity of the MCP, and hypointensity of the putamen. Measurements of the MCP width were performed in all subjects. Results: All patients with MSA had different severity of atrophy in the cerebellum,pons, medulla oblongata and/or putamen. Cruciform hyperintensity of the pons was found in 15 cases with MSA;hyperintensity of the MCP in 6 cases with MSA; slit-like hyperintensity in the posterolateral margin of the putamen in 8 cases with MSA; and hypointensity of the putamen in 4 cases with MSA respectively. The MCP width was significantly smaller in MSA group(6.4±1.4)mm than that in PD group(9.2±1.1) mm or control group(9.4±0.8)mm. The average MCP width in 15 MSA patients with cruciform hyperintensity was significantly lower(5.3±1.0)mm than that in 11 MSA patients without cruciform hyperintensity(7.2±1.6 mm)(P0.05). Conclusion: The MR imaging is useful for diagnosing MSA. Measurement of MCP width on MR images is helpful for distinguishing patients with MSA from those with PD.
【Fund】: 深圳市科技研发资金(No.JCYJ20130402114702121)
【CateGory Index】: R445.2;R741.04
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHONG Xiao-ling;HUANG Biao;YANG Wan-qun;Department of Radiology,Guangdong General Hospital,Guangdong Academy of Medical Sciences;;Area measurement of the pons by MRI in differential diagnosis between cerebellar dominant multiple system atrophy and Parkinson's disease[J];Radiologic Practice;2013-11
2 TANG Xiaohong;CUI Yan;Department of Infection Management, Affiliated to Nanjing Medical University;;Research progress on quality of life in patients with multiple system atrophy[J];Chinese Nursing Management;2014-01
3 Li Shujian,Huang Yue,Dang Lei,et al.Department of Neurology,Henan Provincial People's Hospital,Zhengzhou 450003,China;Clinical and MRI features of multiple system atrophy patients with pontine cross sign[J];Chinese Journal of Practical Nervous Diseases;2011-08
4 WU Wulin, WANG Xiaoyi, LIAO Weihua,et al.Department of Radiology,The Xiangya Hospital,Central South University,Changsha,Hunan Provine 410009,P.R.China;The Value of MRI in Differential Diagnosis between MSA and Parkinson's Disease[J];Journal of Clinical Radiology;2008-06
5 KUANG Lanqiong,WANG Xiaoyi,XING Wu,et al. Department of Radiology,Xiangya Hospital of Central-South University, Changsha,Hunan Province 410008,P.R.China;MRI Features of Multiple System Atrophy P Type[J];Journal of Clinical Radiology;2012-04
6 WANG Bo,ZHANG Chao-dong,LI Zhao.Department of Neurology,the First Hospital Affiliated to China Medical University,Shenyang 110001,China;Features of clinical and progression of multiple system atrophy[J];Journal of Clinical Neurology;2007-06
7 ZHAO Wen-xin, ZHU Wu-sheng, TANG Bing, et al. (Department of Neurology, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, Jiangsu, China);Olivopontocerebellar atrophy with cross sign[J];Journal of Brain and Nervous Diseases;2006-06
8 ZHANG Tong,LIU Rui-chun,LIU Xi-qi Department of Neurology,The Second Hospital of Hebei Medical University Shijiazhuang,050000,China;The clinical manifestations and MRI images of 11 patients with Olivo-ponto-cerebellar atrophy[J];Journal of Brain and Nervous Diseases;2008-04
9 LIN Hua,XIONG Bin,QI Xiao-kun,YAO Sheng,WANG Qi,QIAN Hai-rong.Department of Neurology,Navy General Hospital,People's Liberation Army,Beijing 100048,China;One rare case of neurological paraneoplastic syndrome refered to spinal cord and thalamus[J];Journal of Brain and Nervous Diseases;2012-02
10 CHENG Feng;ZHANG Boai;Department of Neurology,the First Affiliated Hospital of Zhengzhou University;;Clinical analysis of 68 cases with multiple system atrophy[J];Henan Medical Research;2014-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved