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Clinical Efficacy of Assisted Cranial Electrotherapy Stimulation Treatment on Depression

WEI Ying;YANG Zhong;PAN Hui;ZHAO Sheng-jun;FANG Jian-zhong;Department of Psychiatry, The Third People's Hospital of Changshu City;  
Objective: To observe the curative effect and safety of antidepressants combined with Cranial Electrotherapy Stimulation(CES) in treatment for depression patients. Methods: Eighty depression patients were randomly divided into the groups of CES and control equally. The two groups were given antidepressants, and the CES group was received additional CES treatment. All the treatment lasted for 6 weeks. Disease Severity was assessed by Hamilton depression rating scale(HAMD) and Hamilton anxiety scale(HAMA). The cognitive function was assessed by Wisconsin Card Sorting Test(WCST). The safety was evaluated with Treatment Emergent Symptom Scale(TESS). Results: There were 38 cases in the CES group and 37 cases in the control group who had completed 6 study. After the treatment, the HAMD and HAMA scores in the 2 groups were significantly lower than those before the treatment(P0.01). At the sixth week, the assisted efficiency and curative rates between the two groups showed no significant difference(P0.05). At the fourth week, the efficiency in the CES group was significantly higher than that in the control group(P0.05). The comparison of the adverse events between the two group revealed no difference(P0.05). Conclusion: CES in adjuvant treatment of depression is safe and effective.
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